Multiomic Analysis of Neurons with Divergent Projection Patterns Identifies Novel Regulators of Axon Pathfinding
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DOI: 10.1002/advs.202200615
Abstract: Axon pathfinding is a key step in neural circuits formation. However, the transcriptional mechanisms regulating its progression remain poorly understood. The binary decision of crossing or avoiding the midline taken by some neuronal axons during… read more here.
Keywords: analysis neurons; neurons divergent; multiomic analysis; regulators axon ... See more keywords
Multiomic analysis reveals microbiome-related relationships between cocaine use and metabolites
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DOI: 10.1097/qad.0000000000003363
Abstract: Objective: Over 19 million individuals globally have a cocaine use disorder, a significant public health crisis. Cocaine has also been associated with a pro-inflammatory state and recently with imbalances in the intestinal microbiota as compared… read more here.
Keywords: multiomic analysis; reveals microbiome; cocaine use; analysis reveals ... See more keywords
Multiomic analysis of microRNA-mediated regulation reveals a proliferative axis involving miR-10b in fibrolamellar carcinoma
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DOI: 10.1172/jci.insight.154743
Abstract: Fibrolamellar carcinoma (FLC) is an aggressive liver cancer primarily afflicting adolescents and young adults. Most patients with FLC harbor a heterozygous deletion on chromosome 19 that leads to the oncogenic gene fusion, DNAJB1-PRKACA. There are… read more here.
Keywords: mir 10b; multiomic analysis; fibrolamellar carcinoma; flc ... See more keywords