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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7346-0_10
Abstract: Flow cytometry is the most widely used method for detecting and quantifying apoptosis in mammalian cells. The multiparametric nature of flow cytometry allows several apoptotic characteristics to be combined in a single sample, making it…
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Keywords:
flow cytometry;
multiparametric analysis;
analysis apoptosis;
apoptosis ... See more keywords
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Published in 2017 at "SLAS Discovery"
DOI: 10.1177/2472555217719834
Abstract: The intramembrane protease signal peptide peptidase-like 2a (SPPL2a) is a potential drug target for the treatment of autoimmune diseases due to an essential role in B cells and dendritic cells. To screen a library of…
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Keywords:
analysis;
sppl2a inhibitors;
identification sppl2a;
inhibitors multiparametric ... See more keywords
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Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0230022
Abstract: The objective of this study was to regulate the cytotoxicity of cisplatin (cisPt) minimizing its adverse effects. For this purpose, the lowest cisPt concentration needed to obtain a significant positive response in cutaneous squamous cell…
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Keywords:
carcinoma;
cispt;
cisplatin;
multiparametric analysis ... See more keywords
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Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.956112
Abstract: Tegumentary leishmaniasis is a tropical disease caused by protozoa of the genus Leishmania. Clinically, the disease presents a broad spectrum of symptoms, the mechanisms underlying the development of lesions remaining to be fully elucidated. In…
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Keywords:
tegumentary leishmaniasis;
analysis;
host parasite;
multiparametric analysis ... See more keywords
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Published in 2018 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v24.i27.2995
Abstract: Colorectal cancer (CRC) is a heterogeneous disease, with a diverse and plastic immune cell infiltrate. These immune cells play an important role in regulating tumour growth - progression or elimination. Some populations of cells have…
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Keywords:
multiparametric analysis;
immune responses;
colorectal cancer;