Multiple Cryptic Binding Sites are Necessary for Robust Fibronectin Assembly: An In Silico Study
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DOI: 10.1038/s41598-017-18328-4
Abstract: The mechanism of assembly of the extracellular matrix protein fibronectin (FN) into elastic, insoluble fibrils is still poorly understood. FN fibrillogenesis requires cell-generated forces, which expose cryptic FN-FN binding sites buried in FN Type III… read more here.
Keywords: multiple cryptic; cryptic binding; sites necessary; binding ... See more keywords