A mediation analysis for a nonrare dichotomous outcome with sequentially ordered multiple mediators.
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DOI: 10.1002/sim.8485
Abstract: Mediation analyses can help us to understand the biological mechanism in which an exposure or treatment affects an outcome. Single mediator analyses have been used in various applications, but may not be appropriate for analyzing… read more here.
Keywords: outcome; mediation; path specific; sequentially ordered ... See more keywords
Mediation analysis with multiple mediators under unmeasured mediator‐outcome confounding
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DOI: 10.1002/sim.9624
Abstract: It is often of interest in the health and social sciences to investigate the joint mediation effects of multiple post‐exposure mediating variables. Identification of such joint mediation effects generally require no unmeasured confounding of the… read more here.
Keywords: multiple mediators; outcome; unmeasured mediator; mediation ... See more keywords
Decomposition of the Total Effect in the Presence of Multiple Mediators and Interactions.
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DOI: 10.1093/aje/kwx355
Abstract: Mediation analysis allows decomposing a total effect into a direct effect of the exposure on the outcome and an indirect effect operating through a number of possible hypothesized pathways. Recent studies have provided formal definitions… read more here.
Keywords: presence multiple; effect; total effect; decomposition total ... See more keywords
Interventional Effects for Mediation Analysis with Multiple Mediators.
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DOI: 10.1097/ede.0000000000000596
Abstract: The mediation formula for the identification of natural (in)direct effects has facilitated mediation analyses that better respect the nature of the data, with greater consideration of the need for confounding control. The default assumptions on… read more here.
Keywords: direct effects; mediation analysis; mediation; interventional effects ... See more keywords
Path-specific effects in the presence of a survival outcome and causally ordered multiple mediators with application to genomic data
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DOI: 10.1177/09622802221104239
Abstract: Causal multimediation analysis (i.e. the causal mediation analysis with multiple mediators) is critical for understanding the effectiveness of interventions, especially in medical research. Deriving the path-specific effects of exposure on the outcome through a set… read more here.
Keywords: multiple mediators; outcome; path specific; path ... See more keywords