2D MOF Nanosensor-Integrated Digital Droplet Microfluidic Flow Cytometry for In Situ Detection of Multiple miRNAs in Single CTC Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202201779
Abstract: Current circulating tumor cells (CTCs) detection strategies based on surface epithelial markers suffer from low specificity in distinguishing between CTCs and epithelial cells in hematopoietic cell population. Tumor-associated miRNAs within CTCs are emerging as new… read more here.
Keywords: cell; multiple mirnas; detection; single ctc ... See more keywords
In Situ Detection of Nanotoxicity in Living Cells Based on Multiple miRNAs Probed by a Peptide Functionalized Nanoprobe.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c03950
Abstract: The potential toxicity of nanoparticles, especially for clinically applicable ones, has become a critical concern. Technologies that can in situ-evaluate the toxicity of nanoparticles with high sensitivity are urgently needed. In this study, a facile… read more here.
Keywords: multiple mirnas; living cells; detection nanotoxicity; nanotoxicity ... See more keywords
Triple-Input Molecular AND Logic Gates for Sensitive Detection of Multiple miRNAs.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b16812
Abstract: Abnormal miRNA expressions are closely related to the occurrence and development of cancers. It is of great significance to monitor miRNA expression levels for early diagnosis and therapy of the diseases. This study presents two… read more here.
Keywords: multiple mirnas; dna; input molecular; molecular logic ... See more keywords
Programmable Microparticle Array for In Situ Modification and Multiple miRNA Detection.
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DOI: 10.1021/acssensors.2c02158
Abstract: Simultaneous detection of multiple miRNAs of one disease can greatly reduce misdiagnosis and improve the detection rate, which is helpful for early cancer diagnosis. Here, a programmable microparticle-array-based acoustic microchip for in situ simultaneous multiple… read more here.
Keywords: microparticle array; multiple mirnas; detection; programmable microparticle ... See more keywords
LncRNA MACC1-AS1 sponges multiple miRNAs and RNA-binding protein PTBP1
Sign Up to like & getrecommendations! Published in 2019 at "Oncogenesis"
DOI: 10.1038/s41389-019-0182-7
Abstract: Long noncoding RNA (lncRNA) represents a class of endogenous RNAs that regulate gene expression in eukaryotes. To date, the function and underlying mechanism of the majority of mammalian lncRNAs remain unknown. Here, we report that… read more here.
Keywords: multiple mirnas; as1; rna binding; binding protein ... See more keywords
Analysis of common targets for circular RNAs
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DOI: 10.1186/s12859-019-2966-3
Abstract: BackgroundThe studies of functions of circular RNAs (circRNAs) are heavily focused on the regulation of gene expression through interactions with multiple miRNAs. However, the number of predicted target genes is typically overwhelming due to the… read more here.
Keywords: common targets; analysis common; multiple mirnas; circular rnas ... See more keywords