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Published in 2017 at "Hemoglobin"
DOI: 10.1080/03630269.2017.1366917
Abstract: Abstract Thalassemia is the most common monogenic disease, with the highest incidence in Guangxi Zhuang Autonomous Region, People’s Republic of China (PRC). The blood test result was not consistent with α-globin gene testing in one…
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Keywords:
disease caused;
hba2 hba2;
multiple mutations;
signal site ... See more keywords
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Published in 2020 at "Cancer Science"
DOI: 10.1111/cas.14699
Abstract: Recent studies of the cancer genome have identified numerous patients harboring multiple mutations (MM) within individual oncogenes. These MM (de novo MM) in cis synergistically activate the mutated oncogene and promote tumorigenesis, indicating a positive…
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Keywords:
mutations within;
evolution;
multiple mutations;
cancer ... See more keywords
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Published in 2022 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201024666221124151623
Abstract: BACKGROUND Streptokinase, one of the most widely used thrombolytic medicines, is a favorable protein for site-specific PEGylation as it lacks any cysteine residues in its amino acid sequence; however, any changes in the protein´s structure…
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Keywords:
multiple mutations;
mutations domains;
cysteine analogues;
activity ... See more keywords
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Published in 2022 at "Viruses"
DOI: 10.3390/v14122775
Abstract: Genetic analysis of intra-host viral populations provides unique insight into pre-emergent mutations that may contribute to the genotype of future variants. Clinical samples positive for SARS-CoV-2 collected in California during the first months of the…
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Keywords:
multiple mutations;
low frequency;
mutations associated;
sars cov ... See more keywords