LAUSR

Multiple Mutations in the β1 Subunit of the Nicotinic Acetylcholine Receptor Confer Resistance to Neonicotinoids.

Sign Up to like & get
recommendations!
0 Published in 2025 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.5c01017

Abstract: The evolution of resistance to neonicotinoid insecticides threatens global agriculture. To elucidate its molecular basis, we employed Drosophila melanogaster as a model system to investigate resistance-associated mutations in the β1 subunit of nicotinic acetylcholine receptors… read more here.

Keywords: subunit nicotinic; resistance; mutations subunit; nicotinic acetylcholine ... See more keywords

Hb H Disease Caused by Multiple Mutations in the Polyadenylation Signal Site and − −SEA/αα

Sign Up to like & get
recommendations!
1 Published in 2017 at "Hemoglobin"

DOI: 10.1080/03630269.2017.1366917

Abstract: Abstract Thalassemia is the most common monogenic disease, with the highest incidence in Guangxi Zhuang Autonomous Region, People’s Republic of China (PRC). The blood test result was not consistent with α-globin gene testing in one… read more here.

Keywords: disease caused; hba2 hba2; multiple mutations; signal site ... See more keywords

Multiple mutations within individual oncogenes

Sign Up to like & get
recommendations!
0 Published in 2020 at "Cancer Science"

DOI: 10.1111/cas.14699

Abstract: Recent studies of the cancer genome have identified numerous patients harboring multiple mutations (MM) within individual oncogenes. These MM (de novo MM) in cis synergistically activate the mutated oncogene and promote tumorigenesis, indicating a positive… read more here.

Keywords: mutations within; evolution; multiple mutations; cancer ... See more keywords

Multiple mutations on α, β and γ domains of streptokinase lead to the generation of highly efficient cysteine analogues with promising features.

Sign Up to like & get
recommendations!
2 Published in 2022 at "Current pharmaceutical biotechnology"

DOI: 10.2174/1389201024666221124151623

Abstract: BACKGROUND Streptokinase, one of the most widely used thrombolytic medicines, is a favorable protein for site-specific PEGylation as it lacks any cysteine residues in its amino acid sequence; however, any changes in the protein´s structure… read more here.

Keywords: multiple mutations; mutations domains; cysteine analogues; activity ... See more keywords

Multiple Mutations Associated with Emergent Variants Can Be Detected as Low-Frequency Mutations in Early SARS-CoV-2 Pandemic Clinical Samples

Sign Up to like & get
recommendations!
1 Published in 2022 at "Viruses"

DOI: 10.3390/v14122775

Abstract: Genetic analysis of intra-host viral populations provides unique insight into pre-emergent mutations that may contribute to the genotype of future variants. Clinical samples positive for SARS-CoV-2 collected in California during the first months of the… read more here.

Keywords: multiple mutations; low frequency; mutations associated; sars cov ... See more keywords