Multiple Nf1 Schwann cell populations reprogram the plexiform neurofibroma tumor microenvironment
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DOI: 10.1172/jci.insight.154513
Abstract: To define alterations early in tumor formation, we studied nerve tumors in neurofibromatosis 1 (NF1), a tumor predisposition syndrome. Affected individuals develop neurofibromas, benign tumors driven by NF1 loss in Schwann cells (SCs). By comparing… read more here.
Keywords: multiple nf1; plexiform neurofibroma; cell; cell populations ... See more keywords