Nicotinamide Adenine Dinucleotide Supplementation in Parkinson's Disease: A Potential Disease‐Modifying Agent Targeting Multiple Pathways
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13500
Abstract: modi fi cation and neuroprotection are still unmet needs in Parkinson ’ s disease (PD), due to several challenges, including multiple pathogenic the upregulation of genes involved in proteasomal function, mitochondrial homeostasis, and antioxidant function.… read more here.
Keywords: supplementation; nicotinamide adenine; adenine dinucleotide; disease ... See more keywords
Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases
Sign Up to like & getrecommendations! Published in 2017 at "Ageing Research Reviews"
DOI: 10.1016/j.arr.2016.10.008
Abstract: Sirtuin 6 (SIRT6) is a member of the sirtuin family NAD+-dependent deacetylases with multiple roles in controlling organism homeostasis, lifespan, and diseases. Due to its complex and opposite functional roles, this sirtuin is considered a… read more here.
Keywords: multiple pathways; crossroads control; sirt6 crossroads; control longevity ... See more keywords
Topological Analysis Reveals Multiple Pathways in Molecular Dynamics
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Chemical Theory and Computation"
DOI: 10.1021/acs.jctc.5c00819
Abstract: Molecular Dynamics simulations are indispensable tools for comprehending the dynamic behavior of biomolecules, yet extracting meaningful molecular pathways from these simulations remains challenging due to the vast amount of high dimensional data. In this work,… read more here.
Keywords: topological analysis; multiple pathways; molecular dynamics; reveals multiple ... See more keywords
Thiosemicarbazone Mixed-Valence Cu(I/II) Complex against Lung Adenocarcinoma Cells through Multiple Pathways Involving Cuproptosis.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.4c00257
Abstract: Induction of cuproptosis and targeting of multiple signaling pathways show promising applications in tumor therapy. In this study, we synthesized two thiosemicarbazone-copper complexes ([CuII(L)Cl] 1 and [CuII2CuI(L)2Cl3] 2, where HL is the (E)-N-methyl-2-(phenyl(pyridin-2-yl)methylene ligand), to… read more here.
Keywords: cancer; copper complexes; lung; thiosemicarbazone ... See more keywords
Educational Transitions and Educational Inequality: A Multiple Pathways Sequential Logit Model Analysis of Finnish Birth Cohorts 1960–1985
Sign Up to like & getrecommendations! Published in 2020 at "European Sociological Review"
DOI: 10.1093/esr/jcaa019
Abstract: Intergenerational inequality of educational attainment—typically measured by the association between parental socioeconomic characteristics and filial educational attainment—is of major research interest among sociologists and economists alike. Starting from the seminal work by Mare (1981), sociologists… read more here.
Keywords: multiple pathways; transition; model; inequality ... See more keywords
Multiple pathways of integration: Acculturative change and associations with school adjustment in immigrant-origin adolescents.
Sign Up to like & getrecommendations! Published in 2022 at "Child development"
DOI: 10.1111/cdev.13876
Abstract: Tracing developmental pathways of immigrant-origin adolescents, this 3-year longitudinal study (2012-2015) examined within-person changes in cultural orientations and their consequences for school adjustment. Multivariate latent growth mixture modeling confirmed multiple pathways of integration, revealing variable… read more here.
Keywords: origin; immigrant origin; origin adolescents; school adjustment ... See more keywords
Multiple Pathways to Juvenile Recidivism: Examining Parental Drug and Mental Health Problems, and Markers of Neuropsychological Deficits Among Serious Juvenile Offenders
Sign Up to like & getrecommendations! Published in 2017 at "Criminal Justice and Behavior"
DOI: 10.1177/0093854817714810
Abstract: The current study examines multiple pathways to antisocial behavior involving neurobiologically based measures and indicators of executive functioning in the interest of informing treatment and intervention services for the deepest end juvenile justice placements. Specifically,… read more here.
Keywords: multiple pathways; health problems; juvenile; juvenile offenders ... See more keywords
Mathematical modeling of multiple pathways in colorectal carcinogenesis using dynamical systems with Kronecker structure
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1008970
Abstract: Like many other types of cancer, colorectal cancer (CRC) develops through multiple pathways of carcinogenesis. This is also true for colorectal carcinogenesis in Lynch syndrome (LS), the most common inherited CRC syndrome. However, a comprehensive… read more here.
Keywords: multiple pathways; kronecker structure; colorectal carcinogenesis; pathways colorectal ... See more keywords
Multiple pathways of SARS-CoV-2 nosocomial transmission uncovered by integrated genomic and epidemiological analyses during the second wave of the COVID-19 pandemic in the UK
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.1066390
Abstract: Introduction Throughout the global COVID-19 pandemic, nosocomial transmission has represented a major concern for healthcare settings and has accounted for many infections diagnosed within hospitals. As restrictions ease and novel variants continue to spread, it… read more here.
Keywords: nosocomial transmission; transmission; hospital; covid pandemic ... See more keywords
Combined transcriptomic and proteomic analysis reveals multiple pathways involved in self-pollen tube development and the potential roles of FviYABBY1 in self-incompatibility in Fragaria viridis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.927001
Abstract: Fragaria viridis exhibits S-RNase-based gametophytic self-incompatibility, in which S-RNase is the major factor inhibiting pollen tube growth. However, the pathways involved in and the immediate causes of the inhibition of pollen tube growth remain unknown.… read more here.
Keywords: self incompatibility; fragaria viridis; pollen tube; pathways involved ... See more keywords
Transcriptome and Metabolome Analyses Reveal the Involvement of Multiple Pathways in Flowering Intensity in Mango
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.933923
Abstract: Mango (Mangifera indica L.) is famous for its sweet flavor and aroma. China is one of the major mango-producing countries. Mango is known for variations in flowering intensity that impacts fruit yield and farmers' profitability.… read more here.
Keywords: mango; flowering intensity; metabolome analyses; multiple pathways ... See more keywords