Acidity‐Biodegradable Iridium‐Coordinated Nanosheets for Amplified Ferroptotic Cell Death Through Multiple Regulatory Pathways
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202562
Abstract: Ferroptosis‐based treatment strategies display the potential to suppress some malignant tumors with intrinsic apoptosis resistance. However, current related cancer treatments are still hampered by insufficient intracellular reactive oxygen species (ROS) levels and Fe2+ contents, posing… read more here.
Keywords: coordinated nanosheets; regulatory pathways; biodegradable iridium; multiple regulatory ... See more keywords
Multiple regulatory events contribute to a widespread circular RNA downregulation in precancer and early stage of colorectal cancer development
Sign Up to like & getrecommendations! Published in 2025 at "Biomarker Research"
DOI: 10.1186/s40364-025-00744-8
Abstract: Early detection of colorectal cancer (CRC) significantly improves its management and patients’ survival. Circular RNAs (circRNAs) are peculiar covalently closed transcripts involved in gene expression modulation whose dysregulation has been extensively reported in CRC cells.… read more here.
Keywords: colorectal cancer; multiple regulatory; regulatory events; rna ... See more keywords
Succinate utilisation by Salmonella is inhibited by multiple regulatory systems
Sign Up to like & getrecommendations! Published in 2024 at "PLOS Genetics"
DOI: 10.1371/journal.pgen.1011142
Abstract: Succinate is a potent immune signalling molecule that is present in the mammalian gut and within macrophages. Both of these infection niches are colonised by the pathogenic bacterium Salmonella enterica serovar Typhimurium during infection. Succinate… read more here.
Keywords: multiple regulatory; succinate utilisation; salmonella; regulatory systems ... See more keywords