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   Articles with "multiple sclerosis" as a keyword



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Assessment of Efficacy and Tolerability of Medicinal Cannabinoids in Patients With Multiple Sclerosis

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recommendations! Published in 2018 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2018.3485

Abstract: Key Points Question Are medicinal cannabinoids effective and well tolerated in the treatment of multiple sclerosis? Findings In this systematic review and meta-analysis of 17 randomized clinical trials including 3161 patients, cannabinoids were significantly associated… read more here.

Keywords: medicinal cannabinoids; assessment efficacy; multiple sclerosis; adverse events ... See more keywords
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Associations Between Findings From Myelin Water Imaging and Cognitive Performance Among Individuals With Multiple Sclerosis

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recommendations! Published in 2020 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2020.14220

Abstract: Key Points Question Is myelin damage in normal-appearing white matter associated with cognitive impairment in participants with multiple sclerosis (MS)? Findings In this cross-sectional study of 73 participants with MS and 22 age-, sex-, and… read more here.

Keywords: cognitive performance; water imaging; multiple sclerosis; performance ... See more keywords
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Multiple Sclerosis Disease Activity and Disability Following Discontinuation of Natalizumab for Pregnancy

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2021.44750

Abstract: Key Points Question Is early natalizumab cessation before or during the first trimester of pregnancy associated with multiple sclerosis relapse occurrence and relapse-related disability? Findings In this cohort study of 274 pregnancies, relapses during pregnancy… read more here.

Keywords: sclerosis disease; disability; natalizumab cessation; pregnancy ... See more keywords
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Serum Neurofilament Light and Multiple Sclerosis Progression Independent of Acute Inflammation

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2021.47588

Abstract: This cohort study investigates serum neurofilament light concentration as a biomarker associated with disability progression in multiple sclerosis in the absence of acute inflammation. read more here.

Keywords: neurofilament light; progression; acute inflammation; multiple sclerosis ... See more keywords
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Factors Associated With Serological Response to SARS-CoV-2 Vaccination in Patients With Multiple Sclerosis Treated With Rituximab

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.11497

Abstract: Key Points Question Are certain demographic or clinical factors associated with a favorable vaccine response to tozinameran among rituximab-treated patients with multiple sclerosis? Findings In this cohort study of 67 patients with multiple sclerosis, among… read more here.

Keywords: multiple sclerosis; factors associated; patients multiple; serological response ... See more keywords
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Effect of Dimethyl Fumarate vs Interferon β-1a in Patients With Pediatric-Onset Multiple Sclerosis

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recommendations! Published in 2022 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2022.30439

Abstract: This randomized clinical trial investigates the efficacy and safety of dimethyl fumarate vs interferon β-1a for treatment of pediatric-onset multiple sclerosis. read more here.

Keywords: onset multiple; pediatric onset; multiple sclerosis; dimethyl fumarate ... See more keywords
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Considering the Future of Pediatric Multiple Sclerosis Trials After the CONNECT Open-Label Randomized Trial.

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recommendations! Published in 2022 at "JAMA network open"

DOI: 10.1001/jamanetworkopen.2022.30451

Abstract: The approach to treatment of relapsing-remitting multiple sclerosis (RRMS) is rapidly evolving, with more than 15 disease-modifying therapies (DMTs) currently licensed for adults. Current treatment algorithms in children with multiple sclerosis (MS) remain heavily reliant… read more here.

Keywords: sclerosis; future pediatric; considering future; trial ... See more keywords
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Efficacy and Safety of 2 Fingolimod Doses vs Glatiramer Acetate for the Treatment of Patients With Relapsing-Remitting Multiple Sclerosis

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recommendations! Published in 2020 at "JAMA Neurology"

DOI: 10.1001/jamaneurol.2020.2950

Abstract: Key Points Question Is treatment with a fingolimod dose of 0.5 mg or 0.25 mg superior to glatiramer acetate, 20 mg, in reducing relapse activity over 12 months in adult participants aged 18 to 65… read more here.

Keywords: relapsing remitting; treatment; fingolimod; multiple sclerosis ... See more keywords
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Treatment and disease management of multiple sclerosis patients: A review for nurse practitioners

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recommendations! Published in 2017 at "Journal of the American Association of Nurse Practitioners"

DOI: 10.1002/2327-6924.12514

Abstract: Background and purpose This review discusses the role of the nurse practitioner (NP) in evaluating the clinical effects, potential side effects, and monitoring requirements for treatment options in multiple sclerosis (MS) and provides guidance on… read more here.

Keywords: treatment; management; disease management; multiple sclerosis ... See more keywords
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Glioblastoma in natalizumab‐treated multiple sclerosis patients

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recommendations! Published in 2017 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.428

Abstract: We present two natalizumab‐treated multiple sclerosis patients who developed glioblastoma multiforme (GBM) with variable outcomes. One patient had an isocitrate dehydrogenase (IDH)‐wildtype GBM with aggressive behavior, who declined treatment and died 13 weeks after symptoms… read more here.

Keywords: natalizumab treated; gbm; multiple sclerosis; sclerosis patients ... See more keywords
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Infectious risk stratification in multiple sclerosis patients receiving immunotherapy

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recommendations! Published in 2017 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.491

Abstract: The increasing number of potent treatments for multiple sclerosis warrants screening for infections. To investigate the prevalence of infections in two independent German patient cohorts with multiple sclerosis/neuromyelitis optica spectrum disorders (NMOSD), we performed a… read more here.

Keywords: sclerosis; risk stratification; multiple sclerosis; stratification multiple ... See more keywords