Colorectal cancer (CRC) as a multifactorial disease and its causal correlations with multiple signaling pathways
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DOI: 10.1042/bsr20200265
Abstract: Abstract Colorectal cancer (CRC) is the third most common malignancy and one of the leading causes of cancer-related death among men worldwide. CRC is a multifactor digestive pathology, which is a huge problem faced not… read more here.
Keywords: cancer crc; crc; multiple signaling; signaling pathways ... See more keywords
HSD3B1 Expression Is Upregulated by Interleukin 4 in HT-29 Colon Cancer Cells via Multiple Signaling Pathways
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DOI: 10.3390/ijms232113572
Abstract: 3β-Hydroxysteroid dehydrogenase/isomerase is essential for the synthesis of active steroid hormones. Interleukin 4 (IL4) induces the expression of HSD3B1 in various human cancer cell lines. Here, we demonstrated that administration of IL4 to an HT-29… read more here.
Keywords: hsd3b1 expression; expression; colon cancer; multiple signaling ... See more keywords
Thymosin Beta 4 Inhibits LPS and ATP-Induced Hepatic Stellate Cells via the Regulation of Multiple Signaling Pathways
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DOI: 10.3390/ijms24043439
Abstract: Risk signals are characteristic of many common inflammatory diseases and can function to activate nucleotide-binding oligomerization (NLR) family pyrin domain-containing 3 (NLRP3), the innate immune signal receptor in cytoplasm. The NLRP3 inflammasome plays an important… read more here.
Keywords: lps atp; thymosin beta; multiple signaling; hepatic stellate ... See more keywords
Combination of Fish Oil and Selenium Enhances Anticancer Efficacy and Targets Multiple Signaling Pathways in Anti-VEGF Agent Treated-TNBC Tumor-Bearing Mice
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DOI: 10.3390/md19040193
Abstract: Fish oil (FO) and selenium (Se) possess antiangiogenic potential in malignant tumors. This study aimed to determine whether combination of FO and Se enhanced treatment efficacy of low-dose antiangiogenic agent Avastin (bevacizumab) in a dose-dependent… read more here.
Keywords: combination; signaling pathways; oil selenium; multiple signaling ... See more keywords