Articles with "multiplex digital" as a keyword



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Multiplex Digital Methylation‐Specific PCR for Noninvasive Screening of Lung Cancer

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Published in 2023 at "Advanced Science"

DOI: 10.1002/advs.202206518

Abstract: There remains tremendous interest in developing liquid biopsy assays for detection of cancer‐specific alterations, such as mutations and DNA methylation, in cell‐free DNA (cfDNA) obtained through noninvasive blood draws. However, liquid biopsy analysis is often… read more here.

Keywords: methylation; multiplex digital; digital methylation; pcr ... See more keywords

Tracking Different States of Spiked Environmental DNA Using Multiplex Digital PCR Assays

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Published in 2025 at "Environmental Microbiology"

DOI: 10.1111/1462-2920.70086

Abstract: ABSTRACT The study of microbial communities based on the total environmental DNA (eDNA) is influenced by the presence of different eDNA states, i.e., intracellular (iDNA) and extracellular DNA (exDNA), and the choice of the DNA… read more here.

Keywords: pcr assays; digital pcr; multiplex digital; using multiplex ... See more keywords

Multiplex Digital Spatial Profiling in Breast Cancer Research: State-of-the-Art Technologies and Applications across the Translational Science Spectrum

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Published in 2024 at "Cancers"

DOI: 10.3390/cancers16091615

Abstract: Simple Summary Multiplex digital spatial profiling is a newly emerging approach for investigating multiple RNA transcripts and proteins simultaneously in the context of intact tissue. This review describes the different spatial technologies for the study… read more here.

Keywords: cancer; breast cancer; multiplex digital; cancer research ... See more keywords

Optimization and Application of a Multiplex Digital PCR Assay for the Detection of SARS-CoV-2 Variants of Concern in Belgian Influent Wastewater

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Published in 2022 at "Viruses"

DOI: 10.3390/v14030610

Abstract: Since the beginning of the COVID-19 pandemic, the wastewater-based epidemiology (WBE) of SARS-CoV-2 has been used as a complementary indicator to follow up on the trends in the COVID-19 spread in Belgium and in many… read more here.

Keywords: cov variants; wastewater; variants concern; multiplex digital ... See more keywords