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Published in 2022 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2022.339562
Abstract: Multiplexed assays are essential for the detection of biomarker panels. Differentiating signals from different biomarkers in a single test zone makes the detection more efficient. In this paper, a new method is designed for the…
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Keywords:
biomarker;
multiplexed assay;
detection;
gap ... See more keywords
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Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.08.091
Abstract: Chronic metabolic diseases have been linked to molecular signatures of mitochondrial dysfunction. Nonetheless, molecular remodeling of the transcriptome, proteome, and/or metabolome does not necessarily translate to functional consequences that confer physiologic phenotypes. The work here…
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Keywords:
multiplexed assay;
energy;
platform comprehensive;
comprehensive assessment ... See more keywords
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Published in 2019 at "Cell systems"
DOI: 10.1016/j.cels.2019.02.009
Abstract: G protein-coupled receptors (GPCRs) are central to how mammalian cells sense and respond to chemicals. Mammalian olfactory receptors (ORs), the largest family of GPCRs, mediate the sense of smell through activation by small molecules, though…
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Keywords:
multiplexed assay;
scalable multiplexed;
decoding gpcr;
assay decoding ... See more keywords
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Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113844
Abstract: Hereditary angioedema (HAE) is a rare genetic disease caused by deficiency or dysfunction of C1 esterase inhibitor (C1-INH). Plasma C1-INH activity and concentrations of C1-INH and complement components 1q and 4 (C1q, C4) are critical…
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Keywords:
multiplexed assay;
blood spot;
c1q;
dried blood ... See more keywords
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Published in 2021 at "Biopreservation and biobanking"
DOI: 10.1089/bio.2021.0042
Abstract: Microsatellites, or MSATs, offer a fast and cost-effective way for biobanks to establish a biospecimen genetic profile. Importantly, this genetic profile can be used to authenticate multiple submissions derived from the same individual as well…
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Keywords:
multiplexed assay;
new multiplexed;
biobanking new;
markers biobanking ... See more keywords