Multiplexed Isobaric Tag‐Based Profiling of Seven Murine Tissues Following In Vivo Nicotine Treatment Using a Minimalistic Proteomics Strategy
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DOI: 10.1002/pmic.201700326
Abstract: Nicotine is a major addictive compound in tobacco and a component of smoking‐related products, such as e‐cigarettes. Once internalized, nicotine can perturb many cellular pathways and can induce alterations in proteins across different cell types;… read more here.
Keywords: tag based; multiplexed isobaric; proteomics strategy; minimalistic proteomics ... See more keywords
Coupling Microdroplet-Based Sample Preparation, Multiplexed Isobaric Labeling, and Nanoflow Peptide Fractionation for Deep Proteome Profiling of the Tissue Microenvironment
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DOI: 10.1021/acs.analchem.4c00523
Abstract: There is increasing interest in developing in-depth proteomic approaches for mapping tissue heterogeneity in a cell-type-specific manner to better understand and predict the function of complex biological systems such as human organs. Existing spatially resolved… read more here.
Keywords: labeling nanoflow; multiplexed isobaric; nanoflow peptide; deep proteome ... See more keywords