TMT-Based Multiplexed Quantitation of N-Glycopeptides Reveals Glycoproteome Remodeling Induced by Oncogenic Mutations
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c06970
Abstract: Glycoproteomics, or the simultaneous characterization of glycans and their attached peptides, is increasingly being employed to generate catalogs of glycopeptides on a large scale. Nevertheless, quantitative glycoproteomics remains challenging even though isobaric tagging reagents such… read more here.
Keywords: based multiplexed; tmt based; multiplexed quantitation; oncogenic mutations ... See more keywords
Enzyme-mimicking accelerated signal enhancement for visually multiplexed quantitation of telomerase activity.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc01951h
Abstract: Here, we propose an amplification strategy involving enzyme-mimicking accelerated signal enhancement integrated with a triple-channel volumetric bar-chart chip for visually multiplexed quantitation of telomerase activity. This platform was used for evaluating the telomerase activities from… read more here.
Keywords: enzyme mimicking; mimicking accelerated; visually multiplexed; accelerated signal ... See more keywords
Inception and development of a LC-MS/MS assay for the multiplexed quantitation of nine human drug transporter biomarkers.
Sign Up to like & getrecommendations! Published in 2024 at "Bioanalysis"
DOI: 10.4155/bio-2023-0197
Abstract: Background: It has become common practice to assess solute carrier transporter (SLC)-mediated drug-drug interactions (DDIs) by quantitating various individual endogenous compounds as biomarkers in human plasma and urine. The goal of this work was to… read more here.
Keywords: development assay; multiplexed quantitation; drug; inception development ... See more keywords