Quantitative Accuracy and Precision in Multiplexed Single-Cell Proteomics
Sign Up to like & getrecommendations! Published in 2021 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.1c04174
Abstract: Single-cell proteomics workflows have considerably improved in sensitivity and reproducibility to characterize as-yet unknown biological phenomena. With the emergence of multiplexed single-cell proteomics, studies increasingly present single-cell measurements in conjunction with an abundant congruent carrier… read more here.
Keywords: multiplexed single; single cell; cell; cell proteomics ... See more keywords
Profiling of BCLxL Protein Complexes in Non-Small Cell Lung Cancer Cells via Multiplexed Single-Molecule Pull-Down and Co-Immunoprecipitation.
Sign Up to like & getrecommendations! Published in 2024 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.3c05801
Abstract: We introduce multiplexed single-molecule pull-down and co-immunoprecipitation, named m-SMPC, an analysis tool for profiling multiple protein complexes within a single reaction chamber using single-molecule fluorescence imaging. We employed site-selective conjugation of biotin and fluorescent dye… read more here.
Keywords: multiplexed single; protein; cell; bclxl ... See more keywords
Highly multiplexed single-cell in situ RNA and DNA analysis with bioorthogonal cleavable fluorescent oligonucleotides† †Electronic supplementary information (ESI) available: Additional figures, schemes, probe sequences and experimental details. See DOI: 10.1039/c7sc05089e
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Science"
DOI: 10.1039/c7sc05089e
Abstract: Bioorthogonal cleavable fluorescent oligonucleotides have been developed to enable highly multiplexed single-cell in situ RNA and DNA analysis. read more here.
Keywords: single cell; fluorescent oligonucleotides; multiplexed single; highly multiplexed ... See more keywords
A 96.9-dB-Resolution 109-μW Second-Order Robust Closed-Loop VCO-Based Sensor Interface for Multiplexed Single-Ended Resistance Readout in 180-nm CMOS
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Journal of Solid-State Circuits"
DOI: 10.1109/jssc.2022.3163284
Abstract: This article presents a highly digital robust voltage-controlled oscillator (VCO)-based front end for multiplexed single-ended resistive sensor readout applications. The architecture features a modified digital phase-locked loop (DPLL) structure that enables second-order noise shaping without… read more here.
Keywords: multiplexed single; vco; single ended; readout ... See more keywords