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Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6756-8_22
Abstract: Multipotent mesenchymal stromal cells (MSC) derived from both the bone marrow and adipose tissue possess the ability to differentiate into multiple cell lineages, regulate the immune function by secreting numerous bioactive paracrine factors, and hold…
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Keywords:
three dimensional;
mesenchymal stromal;
stromal cells;
reconstruction engineering ... See more keywords
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Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-4009-x
Abstract: We studied the effect of autologous and allogeneic lymphocytes on multipotent mesenchymal stromal cells in co-culture. It is shown that changes in multipotent mesenchymal stromal cells and in lymphocytes did not depend on the source…
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Keywords:
culturing multipotent;
mesenchymal stromal;
stromal cells;
expression ... See more keywords
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Published in 2018 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-018-4218-3
Abstract: Analysis of changes in lymphocyte subpopulations during co-culturing with multipotent mesenchymal stromal cells (MSC) revealed two distinct MSC groups: one group (A) increased HLA-DR expression on lymphocytes during co-culturing and the other (B) did not…
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Keywords:
mesenchymal stromal;
individual differences;
stromal cells;
differences multipotent ... See more keywords
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Published in 2021 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-021-05109-3
Abstract: We studied the effect of intranasal administration of exosomes obtained by culturing of multipotent mesenchymal stromal cells (MMSC) isolated from the Wharton’s jelly of the human umbilical cord on spatial memory of olfactory bulbectomized mice…
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Keywords:
administration;
alzheimer disease;
effect intranasal;
intranasal administration ... See more keywords
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Published in 2017 at "Cytotechnology"
DOI: 10.1007/s10616-017-0186-0
Abstract: Clinical use of multipotent Mesenchymal Stromal Cell (MSC)-based medicinal products requires their production in compliance with Good Manufacturing Practices, thus ensuring that the final drug product meets specifications consistently from batch to batch in terms…
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Keywords:
mesenchymal stromal;
potency;
clinical grade;
potential clinical ... See more keywords
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Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-61167-z
Abstract: Multipotent mesenchymal stromal cells (MSCs) can be considered an accessible therapeutic tool for regenerative medicine. Here, we compared the growth kinetics, immunophenotypic and immunomodulatory properties, gene expression and secretome profile of MSCs derived from human…
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Keywords:
mesenchymal stromal;
neuroregenerative potential;
stromal cells;
multipotent mesenchymal ... See more keywords
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Published in 2020 at "International Journal of Hyperthermia"
DOI: 10.1080/02656736.2020.1758350
Abstract: Abstract Purpose Hyperthermia demonstrated clinical efficacy in multimodal cancer treatment. Multipotent mesenchymal stromal cells (MSCs) as part of the tumor-supporting stroma modulate tumor response and tissue regeneration after hyperthermia. We aimed to investigate the effects…
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Keywords:
mesenchymal stromal;
hyperthermia;
stromal cells;
expression ... See more keywords
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Published in 2017 at "Biochemistry (Moscow)"
DOI: 10.1134/s000629791710008x
Abstract: Multipotent mesenchymal stromal cells (MSCs) are widely used for cell therapy, in particular for prophylaxis and treatment of graft-versus-host disease. Due to their immunomodulatory properties, MSCs affect the composition of lymphocyte subpopulations, which depends on…
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Keywords:
mesenchymal stromal;
mscs mscs;
stromal cells;
mscs ... See more keywords
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Published in 2017 at "Doklady Biochemistry and Biophysics"
DOI: 10.1134/s1607672917050076
Abstract: The Cell-IQ continuous surveillance system allowed us to establish the following changes in a 14- day culture in vitro: a twofold suppression of the directional migration of multipotent mesenchymal stromal cells of human adipose tissue…
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Keywords:
calcium phosphate;
mesenchymal stromal;
cell;
multipotent mesenchymal ... See more keywords
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Published in 2020 at "Doklady Biochemistry and Biophysics"
DOI: 10.1134/s1607672920020052
Abstract: The transcriptomic profile associated with osteo- and adipogenic differentiation in growth-arrested multipotent mesenchymal stromal cells (MSCs) from human adipose tissue was analyzed in vitro at 20% (standard laboratory) and 5% (tissue-related) O2 levels. Compared with…
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Keywords:
bipotent commitment;
differential expression;
multipotent mesenchymal;
stromal cells ... See more keywords
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Published in 2018 at "Molecular Cancer"
DOI: 10.1186/s12943-018-0926-6
Abstract: Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, with high morbidity, relapse and mortality rates. Multipotent mesenchymal stromal cells (MSCs) can be recruited to and become integral components of the HCC…
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Keywords:
hepatocellular carcinoma;
mesenchymal stromal;
stromal cells;
initiation progression ... See more keywords