Articles with "multipotent mesenchymal" as a keyword



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Three-Dimensional Printed Scaffolds with Multipotent Mesenchymal Stromal Cells for Rabbit Mandibular Reconstruction and Engineering.

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Published in 2017 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-6756-8_22

Abstract: Multipotent mesenchymal stromal cells (MSC) derived from both the bone marrow and adipose tissue possess the ability to differentiate into multiple cell lineages, regulate the immune function by secreting numerous bioactive paracrine factors, and hold… read more here.

Keywords: three dimensional; mesenchymal stromal; stromal cells; reconstruction engineering ... See more keywords
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Co-Culturing of Multipotent Mesenchymal Stromal Cells with Autological and Allogenic Lymphocytes

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Published in 2018 at "Bulletin of Experimental Biology and Medicine"

DOI: 10.1007/s10517-018-4009-x

Abstract: We studied the effect of autologous and allogeneic lymphocytes on multipotent mesenchymal stromal cells in co-culture. It is shown that changes in multipotent mesenchymal stromal cells and in lymphocytes did not depend on the source… read more here.

Keywords: culturing multipotent; mesenchymal stromal; stromal cells; expression ... See more keywords
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Individual Differences of Multipotent Mesenchymal Stromal Cells Manifesting in during Interaction with Lymphocytes

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Published in 2018 at "Bulletin of Experimental Biology and Medicine"

DOI: 10.1007/s10517-018-4218-3

Abstract: Analysis of changes in lymphocyte subpopulations during co-culturing with multipotent mesenchymal stromal cells (MSC) revealed two distinct MSC groups: one group (A) increased HLA-DR expression on lymphocytes during co-culturing and the other (B) did not… read more here.

Keywords: mesenchymal stromal; individual differences; stromal cells; differences multipotent ... See more keywords
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Effect of Intranasal Administration of Multipotent Mesenchymal Stromal Cell Exosomes on Memory of Mice in Alzheimer’s Disease Model

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Published in 2021 at "Bulletin of Experimental Biology and Medicine"

DOI: 10.1007/s10517-021-05109-3

Abstract: We studied the effect of intranasal administration of exosomes obtained by culturing of multipotent mesenchymal stromal cells (MMSC) isolated from the Wharton’s jelly of the human umbilical cord on spatial memory of olfactory bulbectomized mice… read more here.

Keywords: administration; alzheimer disease; effect intranasal; intranasal administration ... See more keywords
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Optimisation of a potency assay for the assessment of immunomodulative potential of clinical grade multipotent mesenchymal stromal cells

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Published in 2017 at "Cytotechnology"

DOI: 10.1007/s10616-017-0186-0

Abstract: Clinical use of multipotent Mesenchymal Stromal Cell (MSC)-based medicinal products requires their production in compliance with Good Manufacturing Practices, thus ensuring that the final drug product meets specifications consistently from batch to batch in terms… read more here.

Keywords: mesenchymal stromal; potency; clinical grade; potential clinical ... See more keywords
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A Comparative Analysis of Multipotent Mesenchymal Stromal Cells derived from Different Sources, with a Focus on Neuroregenerative Potential

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-61167-z

Abstract: Multipotent mesenchymal stromal cells (MSCs) can be considered an accessible therapeutic tool for regenerative medicine. Here, we compared the growth kinetics, immunophenotypic and immunomodulatory properties, gene expression and secretome profile of MSCs derived from human… read more here.

Keywords: mesenchymal stromal; neuroregenerative potential; stromal cells; multipotent mesenchymal ... See more keywords
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Multipotent mesenchymal stromal cells are sensitive to thermic stress – potential implications for therapeutic hyperthermia

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Published in 2020 at "International Journal of Hyperthermia"

DOI: 10.1080/02656736.2020.1758350

Abstract: Abstract Purpose Hyperthermia demonstrated clinical efficacy in multimodal cancer treatment. Multipotent mesenchymal stromal cells (MSCs) as part of the tumor-supporting stroma modulate tumor response and tissue regeneration after hyperthermia. We aimed to investigate the effects… read more here.

Keywords: mesenchymal stromal; hyperthermia; stromal cells; expression ... See more keywords
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Effect of priming of multipotent mesenchymal stromal cells with interferon γ on their immunomodulating properties

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Published in 2017 at "Biochemistry (Moscow)"

DOI: 10.1134/s000629791710008x

Abstract: Multipotent mesenchymal stromal cells (MSCs) are widely used for cell therapy, in particular for prophylaxis and treatment of graft-versus-host disease. Due to their immunomodulatory properties, MSCs affect the composition of lymphocyte subpopulations, which depends on… read more here.

Keywords: mesenchymal stromal; mscs mscs; stromal cells; mscs ... See more keywords
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Cell-IQ visualization of motility, cell mass, and osteogenic differentiation of multipotent mesenchymal stromal cells cultured with relief calcium phosphate coating

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Published in 2017 at "Doklady Biochemistry and Biophysics"

DOI: 10.1134/s1607672917050076

Abstract: The Cell-IQ continuous surveillance system allowed us to establish the following changes in a 14- day culture in vitro: a twofold suppression of the directional migration of multipotent mesenchymal stromal cells of human adipose tissue… read more here.

Keywords: calcium phosphate; mesenchymal stromal; cell; multipotent mesenchymal ... See more keywords
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Differential Expression of Bipotent Commitment-Related Genes in Multipotent Mesenchymal Stromal Cells at Different O2 Levels

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Published in 2020 at "Doklady Biochemistry and Biophysics"

DOI: 10.1134/s1607672920020052

Abstract: The transcriptomic profile associated with osteo- and adipogenic differentiation in growth-arrested multipotent mesenchymal stromal cells (MSCs) from human adipose tissue was analyzed in vitro at 20% (standard laboratory) and 5% (tissue-related) O2 levels. Compared with… read more here.

Keywords: bipotent commitment; differential expression; multipotent mesenchymal; stromal cells ... See more keywords
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Multipotent mesenchymal stromal cells play critical roles in hepatocellular carcinoma initiation, progression and therapy

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Published in 2018 at "Molecular Cancer"

DOI: 10.1186/s12943-018-0926-6

Abstract: Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, with high morbidity, relapse and mortality rates. Multipotent mesenchymal stromal cells (MSCs) can be recruited to and become integral components of the HCC… read more here.

Keywords: hepatocellular carcinoma; mesenchymal stromal; stromal cells; initiation progression ... See more keywords