Novel Efficient Multistage Lead Optimization Pipeline Experimentally Validated for DYRK1B Selective Inhibitors
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DOI: 10.1021/acs.jmedchem.2c00988
Abstract: In addition to general challenges in drug discovery such as the identification of lead compounds in time- and cost-effective ways, specific challenges also exist. Particularly, it is necessary to develop pharmacological inhibitors that effectively discriminate… read more here.
Keywords: efficient multistage; lead optimization; novel efficient; optimization pipeline ... See more keywords