Multistate models as a framework for estimand specification in clinical trials of complex processes
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DOI: 10.1002/sim.9675
Abstract: Intensity‐based multistate models provide a useful framework for characterizing disease processes, the introduction of interventions, loss to followup, and other complications arising in the conduct of randomized trials studying complex life history processes. Within this… read more here.
Keywords: multistate models; clinical trials; framework estimand; models framework ... See more keywords
Multistate models for examining the progression of intermittently-measured patient-reported symptoms among cancer patients: the importance of accounting for interval censoring.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pain and symptom management"
DOI: 10.1016/j.jpainsymman.2020.07.012
Abstract: PURPOSE Cancer patients in Ontario, Canada, receive symptom monitoring in a standardized fashion using the Edmonton Symptom Assessment System (ESAS). This paper demonstrates the implementation of multistate models for examining symptom progression, while appropriately accounting… read more here.
Keywords: cancer patients; models examining; multistate models; cancer ... See more keywords
A review of multistate modelling approaches in monitoring disease progression: Bayesian estimation using the Kolmogorov-Chapman forward equations
Sign Up to like & getrecommendations! Published in 2021 at "Statistical Methods in Medical Research"
DOI: 10.1177/0962280221997507
Abstract: There are numerous fields of science in which multistate models are used, including biomedical research and health economics. In biomedical studies, these stochastic continuous-time models are used to describe the time-to-event life history of an… read more here.
Keywords: estimation; multistate models; kolmogorov chapman; chapman forward ... See more keywords
Estimating Working Life Expectancy: A Comparison of Multistate Models
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DOI: 10.1177/21582440231177270
Abstract: Increases in retirement ages make it particularly pressing to better understand how long people will work. Working life expectancy (WLE) is a useful measure for this and the current paper assesses the tools, that is,… read more here.
Keywords: life; working life; life expectancy; multistate models ... See more keywords
The formal demography of kinship II: Multistate models, parity, and sibship
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DOI: 10.4054/demres.2020.42.38
Abstract: Background: Recent kinship models focus on the age structures of kin as a function of the age of the focal individual. However, variables in addition to age have important impacts. Generalizing age-specific models to multistate… read more here.
Keywords: parity; multistate models; age; kinship ... See more keywords