Articles with "multistep synthesis" as a keyword



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Multistep synthesis of a valsartan precursor in continuous flow

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Published in 2019 at "Journal of Flow Chemistry"

DOI: 10.1007/s41981-019-00044-x

Abstract: Valsartan is a potent, orally active angiotensin II receptor blocker and is widely used in the treatment of hypertension and chronic heart failure. Herein, we present an approach for the continuous synthesis of a late-stage… read more here.

Keywords: valsartan precursor; precursor; multistep synthesis; continuous flow ... See more keywords
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Azole-Based Antibacterial Agents: A Review on Multistep Synthesis Strategies and Biology

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Published in 2021 at "Polycyclic Aromatic Compounds"

DOI: 10.1080/10406638.2021.1938615

Abstract: This article reviews current multistep synthesis strategies of azole-based antibacterial agents. In recent years, extensive use of chemical agents in treating different diseases resulted in the dev... read more here.

Keywords: antibacterial agents; synthesis strategies; biology; based antibacterial ... See more keywords