Palladium-Catalyzed Regioselective Carbonylation of 2-Trifluoromethyl-1,3-enynes to Multisubstituted Conjugated Dienes.
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DOI: 10.1021/acs.orglett.2c04331
Abstract: In this communication, a palladium-catalyzed regio- and stereoselective carbonylation of 2-trifluoromethyl-1,3-enynes to afford multisubstituted conjugated dienes has been realized. This protocol features excellent regio- and exclusive (E)-stereoselectivity and a broad substrate scope with both amines… read more here.
Keywords: trifluoromethyl enynes; palladium catalyzed; multisubstituted conjugated; carbonylation trifluoromethyl ... See more keywords