Silica gel-promoted synthesis of multisubstituted spiroindolenines from tryptamines and γ-chloro-α,β-unsaturated ketones
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DOI: 10.1016/j.tet.2020.131765
Abstract: ABSTRACT Here we report a one-pot synthesis of multisubstituted spiroindolenines from a series of tryptamine derivatives with γ-chloro-α,β-unsaturated ketones. The reaction sequence consists of base-induced condensation and silica gel-promoted intramolecular Michael addition. The target molecules… read more here.
Keywords: unsaturated ketones; synthesis multisubstituted; multisubstituted spiroindolenines; chloro unsaturated ... See more keywords