Andrographolide, an Anti-Inflammatory Multitarget Drug: All Roads Lead to Cellular Metabolism
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules26010005
Abstract: Andrographolide is a labdane diterpene and the main active ingredient isolated from the herb Andrographis paniculata. Andrographolide possesses diverse biological effects including anti-inflammatory, antioxidant, and antineoplastic properties. Clinical studies have demonstrated that andrographolide could be… read more here.
Keywords: anti inflammatory; metabolism; andrographolide anti; drug roads ... See more keywords
Multitarget drug design strategy in Alzheimer's disease: focus on cholinergic transmission and amyloid-β aggregation.
Sign Up to like & getrecommendations! Published in 2017 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2017-0039
Abstract: AIM Alzheimer pathogenesis has been associated with a network of processes working simultaneously and synergistically. Over time, much interest has been focused on cholinergic transmission and its mutual interconnections with other active players of the… read more here.
Keywords: cholinergic transmission; drug design; multitarget drug; design strategy ... See more keywords