First dual binder of microRNA-146a and monomeric tau: a novel approach for multitargeted therapeutics for neurodegenerative diseases.
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DOI: 10.1039/d0cc04249h
Abstract: We report a new approach for the development of multitargeted therapeutics for Alzheimer's disease (AD) based on dual targeting of monomeric tau and biogenesis of microRNA-146a. Compound MG-1102 displayed a superior neuroprotective activity, in comparison… read more here.
Keywords: first dual; monomeric tau; multitargeted therapeutics; microrna 146a ... See more keywords