Bioactive Polymeric Scaffolds: Multivalent Functionalization by Thermal Azide–Alkyne Cycloaddition with Alkynyl Dicarbamates
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DOI: 10.1021/acs.biomac.5c00038
Abstract: Multivalency enables interactions with higher affinities and specificities than monovalent interactions. The strategy exploited by nature to modulate biorecognition has inspired the design of multivalent conjugates with therapeutic properties. However, chemical functionalization often requires coupling… read more here.
Keywords: alkyne cycloaddition; alkynyl dicarbamates; multivalent functionalization; functionalization ... See more keywords