Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies
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DOI: 10.1126/sciadv.abm0220
Abstract: Conventional approaches to isolate and characterize nanobodies are laborious. We combine phage display, multivariate enrichment, next-generation sequencing, and a streamlined screening strategy to identify numerous anti–severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nanobodies. We characterize… read more here.
Keywords: immune repertoire; multivariate mining; alpaca immune; mining alpaca ... See more keywords