Articles with "multivesicular body" as a keyword



The regulation of Endosomal Sorting Complex Required for Transport and accessory proteins in multivesicular body sorting and enveloped viral budding - An overview.

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Published in 2019 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2019.01.015

Abstract: ESCRT (Endosomal Sorting Complex Required for Transport) machinery drives different cellular processes such as endosomal sorting, organelle biogenesis, vesicular trafficking, maintenance of plasma membrane integrity, membrane fission during cytokinesis and enveloped virus budding. The normal… read more here.

Keywords: multivesicular body; endosomal sorting; complex required; viral budding ... See more keywords

Real-time imaging of multivesicular body–plasma membrane fusion to quantify exosome release from single cells

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Published in 2019 at "Nature Protocols"

DOI: 10.1038/s41596-019-0245-4

Abstract: Exosomes are small extracellular vesicles with a diameter of 40–150 nm, and are implicated in cellular homeostasis and cell–cell communication. They can be secreted in bulk in response to cell-extrinsic and cell-intrinsic signals that cause… read more here.

Keywords: multivesicular body; exosome release; single cells; fusion ... See more keywords

Phosphatidylinositol-3-phosphate mediates Arc capsid secretion through the multivesicular body pathway

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Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2322422121

Abstract: Significance Activity-regulated cytoskeleton-associated protein (Arc) serves as a pivotal regulator for neuronal communication, influencing both local synaptic transmission and long-range intercellular signaling through direct material exchange. However, the mechanism governing the assembly and secretion pathways… read more here.

Keywords: phosphatidylinositol phosphate; arc capsid; assembly secretion; secretion ... See more keywords