Vascular leakage caused by loss of Akt1 is associated with impaired mural cell coverage
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12621
Abstract: Angiogenesis plays a critical role in embryo development, tissue repair, tumor growth and wound healing. In the present study, we investigated the role of the serine/threonine kinase Akt in angiogenesis. Silencing of Akt1 in human… read more here.
Keywords: angiogenesis; mural cell; akt1; cell coverage ... See more keywords
Insights into cerebral haemodynamics and oxygenation utilising in vivo mural cell imaging and mathematical modelling
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-19086-z
Abstract: The neurovascular mechanisms underpinning the local regulation of cerebral blood flow (CBF) and oxygen transport remain elusive. In this study we have combined novel in vivo imaging of cortical microvascular and mural cell architecture with… read more here.
Keywords: insights cerebral; oxygenation; mural cell; blood ... See more keywords
New models to study vascular mural cell embryonic origin: implications in vascular diseases
Sign Up to like & getrecommendations! Published in 2018 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvy005
Abstract: A key question in vascular biology is how the diversity of origin of vascular mural cells, namely smooth muscle cells (SMCs) and pericytes influences vessel properties, in particular the regional propensity to vascular diseases. This… read more here.
Keywords: vascular mural; mural cell; embryonic origin; vascular diseases ... See more keywords
Notch Signaling in Vascular Endothelial and Mural Cell Communications.
Sign Up to like & getrecommendations! Published in 2022 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a041159
Abstract: The Notch signaling pathway is a highly versatile and evolutionarily conserved mechanism with an important role in cell fate determination. Notch signaling plays a vital role in vascular development, regulating several fundamental processes such as… read more here.
Keywords: notch signaling; cell; endothelial mural; signaling vascular ... See more keywords
Excessive Production of Transforming Growth Factor β1 Causes Mural Cell Depletion From Cerebral Small Vessels
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2020.00151
Abstract: It is increasingly becoming apparent that cerebrovascular dysfunction contributes to the pathogenic processes involved in vascular dementia, Alzheimer’s disease, and other neurodegenerative disorders. Under these pathologic conditions, the degeneration of cerebral blood vessels is frequently… read more here.
Keywords: mural cells; transforming growth; mural cell; growth factor ... See more keywords
Zebrafish Vascular Mural Cell Biology: Recent Advances, Development, and Functions
Sign Up to like & getrecommendations! Published in 2021 at "Life"
DOI: 10.3390/life11101041
Abstract: Recruitment of mural cells to the vascular wall is essential for forming the vasculature as well as maintaining proper vascular functions. In recent years, zebrafish genetic tools for mural cell biology have improved substantially. Fluorescently… read more here.
Keywords: zebrafish mural; cell biology; mural cell; biology ... See more keywords