Separate optogenetic manipulation of Nerve/glial antigen 2 (NG2) glia and mural cells using the NG2 promoter
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24273
Abstract: Nerve/glial antigen 2 (NG2) is a protein marker of NG2 glia and mural cells, and NG2 promoter activity is utilized to target these cells. However, the NG2 promoter cannot target NG2 glia and mural cells… read more here.
Keywords: ng2 promoter; tta; mural cells; ng2 glia ... See more keywords
PDGFRb+ mesenchymal cells, but not NG2+ mural cells, contribute to cardiac fat.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.108697
Abstract: Understanding cellular origins of cardiac adipocytes (CAs) can offer important implications for the treatment of fat-associated cardiovascular diseases. Here, we perform lineage tracing studies by using various genetic models and find that cardiac mesenchymal cells… read more here.
Keywords: mural cells; pdgfrb mesenchymal; intramyocardial adipocytes; mesenchymal cells ... See more keywords
Development of Mural Cells: From In Vivo Understanding to In Vitro Recapitulation
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DOI: 10.1089/scd.2017.0020
Abstract: Mural cells are indispensable for the development and maintenance of healthy mature vasculature, valuable for vascular therapies and as developmental models. However, their functional plasticity, developmental diversity, and multitude of differentiation pathways complicate in vitro… read more here.
Keywords: vivo understanding; cells vivo; mural cells; development mural ... See more keywords
Excessive Production of Transforming Growth Factor β1 Causes Mural Cell Depletion From Cerebral Small Vessels
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2020.00151
Abstract: It is increasingly becoming apparent that cerebrovascular dysfunction contributes to the pathogenic processes involved in vascular dementia, Alzheimer’s disease, and other neurodegenerative disorders. Under these pathologic conditions, the degeneration of cerebral blood vessels is frequently… read more here.
Keywords: mural cells; transforming growth; mural cell; growth factor ... See more keywords
CD146+ mural cells from infantile hemangioma display proangiogenic ability and adipogenesis potential in vitro and in xenograft models
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1063673
Abstract: Objective Infantile hemangioma (IH), the most common infantile vascular neoplasm, is uniquely characterized by rapid proliferation followed by slow spontaneous involution lasting for years. In IH lesions, perivascular cells are the most dynamic cell subset… read more here.
Keywords: infantile hemangioma; hemmcs; weeks implantation; cd146 mural ... See more keywords