Shifting the Focus of Preclinical, Murine Atherosclerosis Studies From Prevention to Late-Stage Intervention.
Sign Up to like & getrecommendations! Published in 2017 at "Circulation research"
DOI: 10.1161/circresaha.116.310101
Abstract: Could improving the design of preclinical murine atherosclerosis studies help increase the success rate of cardiovascular clinical trials? In this Viewpoint, the authors advocate for a change from prevention to intervention study designs and rigorous… read more here.
Keywords: late stage; murine atherosclerosis; atherosclerosis studies; preclinical murine ... See more keywords
Smooth muscle cells affect differential nanoparticle accumulation in disturbed blood flow-induced murine atherosclerosis
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0260606
Abstract: Atherosclerosis is a lipid-driven chronic inflammatory disease that leads to the formation of plaques in the inner lining of arteries. Plaques form over a range of phenotypes, the most severe of which is vulnerable to… read more here.
Keywords: accumulation; wss; muscle cells; atherosclerosis ... See more keywords