Screening of Prototype Antiseizure and Anti-Inflammatory Compounds in the Theiler's Murine Encephalomyelitis Virus Model of Epilepsy.
Sign Up to like & getrecommendations! Published in 2021 at "Epilepsia open"
DOI: 10.1002/epi4.12550
Abstract: OBJECTIVE Infection with Theiler's Murine Encephalomyelitis Virus (TMEV) in C57Bl/6J mice results in handling-induced seizures and is useful for evaluating compounds effective against infection-induced seizures. However, to date only a few compounds have been evaluated… read more here.
Keywords: anti inflammatory; encephalomyelitis virus; murine encephalomyelitis; inflammatory compounds ... See more keywords
Gut dysbiosis and neuroimmune responses to brain infection with Theiler’s murine encephalomyelitis virus
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DOI: 10.1038/srep44377
Abstract: Recent studies have begun to point out the contribution of microbiota to multiple sclerosis (MS) pathogenesis. Theiler’s murine encephalomyelitis virus induced demyelinating disease (TMEV-IDD) is a model of progressive MS. Here, we first analyze the… read more here.
Keywords: encephalomyelitis virus; murine encephalomyelitis; tmev; theiler murine ... See more keywords
Facets of Theiler’s Murine Encephalomyelitis Virus-Induced Diseases: An Update
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DOI: 10.3390/ijms20020448
Abstract: Theiler’s murine encephalomyelitis virus (TMEV), a naturally occurring, enteric pathogen of mice is a Cardiovirus of the Picornaviridae family. Low neurovirulent TMEV strains such as BeAn cause a severe demyelinating disease in susceptible SJL mice… read more here.
Keywords: encephalomyelitis virus; murine encephalomyelitis; induced diseases; theiler murine ... See more keywords