Murine and Human Mammary Cancer Cell Lines: Functional Tests.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8600-2_17
Abstract: The biological characterization of mammary cancer cells is a prerequisite that helps the scientist understand some aspect of tumor biology. Once isolated from the tumor, cells are subjected to multiple tests that dissect their ability… read more here.
Keywords: human mammary; biology; cancer cell; murine human ... See more keywords
Murine and human pancreatic tumor exosome recovery in mouse serum: Diagnostic and prognostic potential and target cell delivery.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.06.005
Abstract: Exosomes (Exo), powerful intercellular communicators, are recovered in all body fluids, suggesting suitability for diagnosis and prognosis. Easy in vitro manipulation recommends Exo as drug vehicles. Aiming to consolidate diagnostic and therapeutic potential of Exo, we… read more here.
Keywords: recovery; serum; human pancreatic; potential ... See more keywords
Organotypic culture assays for murine and human primary and metastatic-site tumors
Sign Up to like & getrecommendations! Published in 2020 at "Nature Protocols"
DOI: 10.1038/s41596-020-0335-3
Abstract: Cancer invasion and metastasis are challenging to study in vivo since they occur deep inside the body over extended time periods. Organotypic 3D culture of fresh tumor tissue enables convenient real-time imaging, genetic and microenvironmental… read more here.
Keywords: organotypic culture; primary metastatic; human primary; metastatic site ... See more keywords
Biglycan as a potential regulator of tumorgenicity and immunogenicity in K-RAS-transformed cells
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2069214
Abstract: ABSTRACT The extracellular matrix component biglycan (BGN) plays an essential role in various physiological and pathophysiological processes. A deficient BGN expression associated with reduced immunogenicity was found in HER-2/neu-overexpressing cells. To determine whether BGN is… read more here.
Keywords: bgn; immunogenicity; ras transformed; expression ... See more keywords
mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming
Sign Up to like & getrecommendations! Published in 2024 at "eLife"
DOI: 10.1101/2023.10.02.560571
Abstract: Alterations in the function of K+ channels such as the voltage- and Ca2+ activated K+ channel of large conductance (BKCa) reportedly promote breast cancer (BC) development and progression. Underlying molecular mechanisms remain, however, elusive. Here,… read more here.
Keywords: murine human; breast cancer; mitobkca; bkca ... See more keywords
Doxorubicin Induces a Senescent Phenotype in Murine and Human Astrocytes
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.70177
Abstract: Aging is a complex biological process that significantly impacts the central nervous system (CNS). Astrocytes, critical support cells in the brain, undergo senescence with age, contributing to neurodegenerative diseases. While previous studies have utilized murine… read more here.
Keywords: senescence; age; murine human; senescent phenotype ... See more keywords
Integration of Murine and Human Studies for Mapping Periodontitis Susceptibility
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Dental Research"
DOI: 10.1177/0022034517744189
Abstract: Periodontitis is one of the most common inflammatory human diseases with a strong genetic component. Due to the limited sample size of available periodontitis cohorts and the underlying trait heterogeneity, genome-wide association studies (GWASs) of… read more here.
Keywords: susceptibility; association; integration murine; human studies ... See more keywords
Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis
Sign Up to like & getrecommendations! Published in 2018 at "Respiratory Research"
DOI: 10.1186/s12931-018-0876-y
Abstract: BackgroundIdiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease. Repetitive injury and reprogramming of the lung epithelium are thought to be critical drivers of disease progression, contributing to fibroblast activation, extracellular matrix remodeling, and… read more here.
Keywords: function; murine human; epithelial cell; lung ... See more keywords
Toxoplasma gondii virulence factor ROP1 reduces parasite susceptibility to murine and human innate immune restriction
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1011021
Abstract: Toxoplasma gondii is an intracellular parasite that can infect many host species and is a cause of significant human morbidity worldwide. T. gondii secretes a diverse array of effector proteins into the host cell which… read more here.
Keywords: rop1; virulence; gondii; innate immune ... See more keywords
T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Oncotarget"
DOI: 10.18632/oncotarget.10298
Abstract: A recent neoadjuvant vaccine trial for early breast cancer induced strong Th1 immunity against the HER-2 oncodriver, complete pathologic responses in 18% of subjects, and for many individuals, dramatically reduced HER-2 expression on residual disease.… read more here.
Keywords: murine human; loss; expression; breast cancer ... See more keywords
Significant Differences in Host-Pathogen Interactions Between Murine and Human Whole Blood
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.565869
Abstract: Murine infection models are widely used to study systemic candidiasis caused by C. albicans. Whole-blood models can help to elucidate host-pathogens interactions and have been used for several Candida species in human blood. We adapted… read more here.
Keywords: human whole; murine blood; blood; murine human ... See more keywords