Articles with "murine macrophages" as a keyword



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The histone deacetylase Hdac7 supports LPS‐inducible glycolysis and Il‐1β production in murine macrophages via distinct mechanisms

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Published in 2021 at "Journal of Leukocyte Biology"

DOI: 10.1002/jlb.2mr1021-260r

Abstract: TLRs reprogram macrophage metabolism, enhancing glycolysis and promoting flux through the tricarboxylic acid cycle to enable histone acetylation and inflammatory gene expression. The histone deacetylase (HDAC) family of lysine deacetylases regulates both TLR‐inducible glycolysis and… read more here.

Keywords: histone deacetylase; murine macrophages; histone; inducible glycolysis ... See more keywords
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Effect of nifedipine, a calcium channel blocker, on the generation of nitric oxide and interleukin-1β by murine macrophages activated by lipopolysaccharide from Prevotella intermedia

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Published in 2020 at "Naunyn-Schmiedeberg's Archives of Pharmacology"

DOI: 10.1007/s00210-020-01958-3

Abstract: Nifedipine, a calcium channel blocker, has been reported to possess anti-inflammatory and immunosuppressive effects. The current study was undertaken to explore the influence of nifedipine on the generation of proinflammatory mediators by murine macrophages activated… read more here.

Keywords: murine macrophages; generation; macrophages activated; intermedia ... See more keywords
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Effect of nitric oxide-releasing derivative of indomethacin on Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages.

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Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.08.055

Abstract: The purpose of this study was to investigate the influences of NCX 2121, a nitric oxide (NO)-releasing derivative of indomethacin, upon the generation of proinflammatory mediators using murine macrophages activated by lipopolysaccharide (LPS) isolated from… read more here.

Keywords: ncx 2121; murine macrophages; indomethacin; intermedia lps ... See more keywords
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The emulsion made with essential oil and aromatic water from Oliveria decumbens protects murine macrophages from LPS-induced oxidation and exerts relevant radical scavenging activities

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Published in 2019 at "Biocatalysis and Agricultural Biotechnology"

DOI: 10.1016/j.bcab.2019.01.015

Abstract: Abstract Oliveria decumbens Vent., is an endemic plant of Iran belonging to the Apiaceae family, where it grows in the arid southeastern regions. In the traditional medicine, it is used in cases of indigestion, diarrhea,… read more here.

Keywords: oliveria decumbens; murine macrophages; essential oil; aromatic water ... See more keywords
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Study on the immunomodulatory activity of a novel polysaccharide from the lichen Umbilicaria Esculenta.

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Published in 2019 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2018.10.080

Abstract: Umbilicaria esculenta possesses nutritional properties, such as antioxidant, antithrombotic and lipid peroxidation inhibitory activity. The immune effects of its polysaccharide (Umbilicaria esculenta polysaccharide, UEP) on murine macrophages RAW264.7 were investigated for the first time. UEP… read more here.

Keywords: study immunomodulatory; murine macrophages; umbilicaria esculenta; polysaccharide ... See more keywords
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Effects of gallic acid on signaling kinases in murine macrophages and immune modulation against Brucella abortus 544 infection in mice.

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Published in 2018 at "Microbial pathogenesis"

DOI: 10.1016/j.micpath.2018.04.032

Abstract: In this study, we investigated the effects of gallic acid (GA) in intracellular signaling within murine macrophages and its contribution to host immunity during Brucella infection. In vitro analysis revealed that GA treatment decreased F-actin… read more here.

Keywords: brucella; gallic acid; infection; murine macrophages ... See more keywords
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Molecular characterization of a novel GSTO2 of Fasciola hepatica and its roles in modulating murine macrophages

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Published in 2022 at "Parasite"

DOI: 10.1051/parasite/2022016

Abstract: Fascioliasis is an important zoonotic helminthic disease caused by Fasciola hepatica and poses a serious threat to global public health. To evade the immune response of its host (humans or animals), F. hepatica secretes various… read more here.

Keywords: fasciola hepatica; hepatica; rgsto2 protein; murine macrophages ... See more keywords
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Anti-inflammatory action of ark shell (Scapharca subcrenata) protein hydrolysate in LPS-stimulated RAW264.7 murine macrophages.

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Published in 2022 at "Journal of food biochemistry"

DOI: 10.1111/jfbc.14493

Abstract: Potential anti-inflammatory effects of ark shell (Scapharca subcrenata) protein hydrolysates were investigated. Ark shell protein hydrolysates were prepared using Alcalase® and pepsin and were designated ASAH and ASPH, respectively. The nitric oxide (NO) inhibitory activity… read more here.

Keywords: raw264 murine; anti inflammatory; murine macrophages; ark shell ... See more keywords
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Treatment with Commelina communis Extract Exerts Anti-inflammatory Effects in Murine Macrophages via Modulation of the Nuclear Factor-κB Pathway

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Published in 2022 at "Mediators of Inflammation"

DOI: 10.1155/2022/2028514

Abstract: The incidence of severe inflammatory diseases caused by chronic inflammation has increased owing to unprecedented changes brought about by industrialization. In this study, we aimed to assess the effect of treatment of lipopolysaccharide- (LPS-) induced… read more here.

Keywords: anti inflammatory; factor; murine macrophages; commelina communis ... See more keywords
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Light Emitting Diode Photobiomodulation Enhances Oxidative Redox Capacity in Murine Macrophages Stimulated with Bothrops jararacussu Venom and Isolated PLA2s

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Published in 2022 at "BioMed Research International"

DOI: 10.1155/2022/5266211

Abstract: Photobiomodulation therapy associated with conventional antivenom treatment has been shown to be effective in reducing the local effects caused by bothropic venoms in preclinical studies. In this study, we analyzed the influence of photobiomodulation using… read more here.

Keywords: jararacussu venom; light emitting; photobiomodulation; murine macrophages ... See more keywords
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IRF1 Is Required for MDA5 (IFIH1) Induction by IFN-α, LPS, and poly(I:C) in Murine Macrophages.

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Published in 2022 at "Journal of innate immunity"

DOI: 10.1159/000527008

Abstract: Melanoma differentiation-associated protein 5 (MDA5) induces type I interferons (IFNs) after the recognition of viral RNA. In addition, gain-of-function mutations in the interferon induced with helicase C domain 1 (IFIH1) gene, which encodes MDA5, lead… read more here.

Keywords: murine macrophages; induction ifn; mda5; induction ... See more keywords