Allogeneic murine pregnancy models for assessing the developmental effects of immune-stimulating antibodies: Challenges in reproducibility.
Sign Up to like & getrecommendations! Published in 2019 at "Birth defects research"
DOI: 10.1002/bdr2.1542
Abstract: Literature suggests that murine allogeneic pregnancy models are an alternative approach for evaluating the developmental toxicity of immune-stimulating agents. In this study, multiple syngeneic and allogeneic murine pregnancy models were used to assess the potential… read more here.
Keywords: murine pregnancy; pregnancy; allogeneic murine; immune stimulating ... See more keywords
Maternal choline supplementation during murine pregnancy modulates placental markers of inflammation, apoptosis and vascularization in a fetal sex-dependent manner.
Sign Up to like & getrecommendations! Published in 2017 at "Placenta"
DOI: 10.1016/j.placenta.2017.03.019
Abstract: INTRODUCTION Normal placental vascular development is influenced by inflammatory, angiogenic and apoptotic processes, which may be modulated by choline through its role in membrane biosynthesis, cellular signaling and gene expression regulation. The current study examined… read more here.
Keywords: murine pregnancy; choline; expression; fetal sex ... See more keywords
Regulatory B cells with IL‐35 and IL‐10 expression in a normal and abortion‐prone murine pregnancy model
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DOI: 10.1111/aji.13217
Abstract: Interleukin 35 is a relatively newly discovered cytokine that is produced by regulatory B cells (Bregs) and contributes to their suppressive function, which may contribute to fetal tolerance development and pregnancy maintenance. Therefore, the aim… read more here.
Keywords: murine pregnancy; normal abortion; pregnancy; abortion prone ... See more keywords
Uterine B Cells Exhibit Regulatory Properties During the Peri-Implantation Stage of Murine Pregnancy
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.02899
Abstract: A successful outcome to pregnancy is dependent on the ability of the maternal uterine microenvironment to regulate inflammation processes and establish maternal tolerance. Recently, B cells have been shown to influence pregnancy outcomes as aberrations… read more here.
Keywords: murine pregnancy; uterine cells; pregnancy; peri implantation ... See more keywords