Skeletal Muscle Aging Atrophy: Assessment and Exercise-Based Treatment.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-42667-5_6
Abstract: In the ordinary course of aging, individuals change their body composition, mainly reducing their skeletal muscle mass and increasing their fat mass. In association, muscle strength and functionality also decrease. The geriatric assessment allows knowing… read more here.
Keywords: skeletal muscle; atrophy; muscle; muscle aging ... See more keywords
Beta-Catenin and SMAD3 Are Associated with Skeletal Muscle Aging in the Taurine Transpoeter Knockout Mouse.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-94-024-1079-2_39
Abstract: Tissue taurine depletion mediated by knocking out the taurine transporter causes several skeletal muscle abnormalities, including acceleration of cellular aging. In the present study, we investigated the signaling pathway involved in the acceleration of skeletal… read more here.
Keywords: skeletal muscle; muscle; catenin; smad3 ... See more keywords
The linear ubiquitin E3 ligase-Relish pathway is involved in the regulation of proteostasis in Drosophila muscle during aging.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.02.135
Abstract: Linear ubiquitination is an atypic ubiquitination process that directly connects the N- and C-termini of ubiquitin and is catalyzed by HOIL-1-interacting protein (HOIP). It is involved in the immune response or apoptosis by activating the… read more here.
Keywords: lubel; muscle; ubiquitin ligase; linear ubiquitin ... See more keywords
The clinical impact and biological mechanisms of skeletal muscle aging.
Sign Up to like & getrecommendations! Published in 2019 at "Bone"
DOI: 10.1016/j.bone.2019.05.021
Abstract: Skeletal muscle is a highly plastic tissue that remarkably adapts to diverse stimuli including exercise, injury, disuse, and, as discussed here, aging. Humans achieve peak skeletal muscle mass and strength in mid-life and then experience… read more here.
Keywords: skeletal muscle; muscle; clinical impact; biological mechanisms ... See more keywords
Declined expressions of vast mitochondria-related genes represented by CYCS and transcription factor ESRRA in skeletal muscle aging.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1948951
Abstract: Age-related skeletal muscle deterioration (sarcopenia) has a significant effect on the elderly's health and quality of life, but the molecular and gene regulatory mechanisms remain largely unknown. It is necessary to identify the candidate genes… read more here.
Keywords: skeletal muscle; muscle; transcription factor; related genes ... See more keywords
Comparative proteomic profiling reveals a role for Cisd2 in skeletal muscle aging
Sign Up to like & getrecommendations! Published in 2018 at "Aging Cell"
DOI: 10.1111/acel.12705
Abstract: Skeletal muscle has emerged as one of the most important tissues involved in regulating systemic metabolism. The gastrocnemius is a powerful skeletal muscle composed of predominantly glycolytic fast‐twitch fibers that are preferentially lost among old… read more here.
Keywords: skeletal muscle; muscle; cisd2; gastrocnemius ... See more keywords
UNC‐120/SRF independently controls muscle aging and lifespan in Caenorhabditis elegans
Sign Up to like & getrecommendations! Published in 2018 at "Aging Cell"
DOI: 10.1111/acel.12713
Abstract: Aging is commonly defined as the loss of global homeostasis, which results from progressive alteration of all organs function. This model is currently challenged by recent data showing that interventions that extend lifespan do not… read more here.
Keywords: unc 120; 120 srf; muscle; caenorhabditis elegans ... See more keywords
The Effect of Metabolites on Mitochondrial Functions in the Pathogenesis of Skeletal Muscle Aging
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Interventions in Aging"
DOI: 10.2147/cia.s376668
Abstract: Abstract Sarcopenia is an age-related systemic disease characterized by skeletal muscle aging that generally severely affects the quality of life of elderly patients. Metabolomics analysis is a powerful tool for qualitatively and quantitatively characterizing the… read more here.
Keywords: effect metabolites; skeletal muscle; muscle; metabolites mitochondrial ... See more keywords
Sarcopenia and Muscle Aging: A Brief Overview.
Sign Up to like & getrecommendations! Published in 2020 at "Endocrinology and metabolism"
DOI: 10.3803/enm.2020.405
Abstract: The world is facing the new challenges of an aging population, and understanding the process of aging has therefore become one of the most important global concerns. Sarcopenia is a condition which is defined by… read more here.
Keywords: sarcopenia; sarcopenia muscle; aging brief; muscle ... See more keywords