Deep learning for the rapid automatic quantification and characterization of rotator cuff muscle degeneration from shoulder CT datasets
Sign Up to like & getrecommendations! Published in 2020 at "European Radiology"
DOI: 10.1007/s00330-020-07070-7
Abstract: Objectives This study aimed at developing a convolutional neural network (CNN) able to automatically quantify and characterize the level of degeneration of rotator cuff (RC) muscles from shoulder CT images including muscle atrophy and fatty… read more here.
Keywords: muscle; atrophy fatty; shoulder; muscle degeneration ... See more keywords
3D analysis of fatty infiltration of the paravertebral lumbar muscles using T2 images—a new approach
Sign Up to like & getrecommendations! Published in 2021 at "European Spine Journal"
DOI: 10.1007/s00586-021-06810-7
Abstract: Factors influencing paraspinal muscle degeneration are still not well understood. Fatty infiltration is known to be one main feature of the degeneration cascade. The aim of this cross-sectional study was to illustrate the 3D cluster… read more here.
Keywords: fatty infiltration; lumbar; muscle degeneration; degeneration ... See more keywords
New MR-based measures for the evaluation of age-related lumbar paraspinal muscle degeneration
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DOI: 10.1007/s00586-021-06811-6
Abstract: Although signal intensity on T2W axial images is sensitive in detection of fatty infiltration to assess paraspinal muscle degeneration, it is affected by inhomogeneities of magnetic fields and individual variabilities. The purpose of this study… read more here.
Keywords: paraspinal muscle; age; muscle degeneration; age related ... See more keywords
STIM1 R304W causes muscle degeneration and impaired platelet activation in mice.
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DOI: 10.1016/j.ceca.2018.10.001
Abstract: STIM1 and ORAI1 regulate store-operated Ca2+ entry (SOCE) in most cell types, and mutations in these proteins have deleterious and diverse effects. We established a mouse line expressing the STIM1 R304 W gain-of-function mutation causing Stormorken… read more here.
Keywords: stim1; platelet activation; muscle degeneration; impaired platelet ... See more keywords
FAPs linked with muscle degeneration in T2DM
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DOI: 10.1038/s41574-021-00601-2
Abstract: 0123456789();: “In relation to T2DM, we need to investigate if the accumulation of FAPs and fibro-fatty degeneration is truly a consequence of T2DM or if it is also involved in the initial development of insulin… read more here.
Keywords: t2dm; faps linked; muscle degeneration; linked muscle ... See more keywords
DRP-1-mediated apoptosis induces muscle degeneration in dystrophin mutants
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DOI: 10.1038/s41598-018-25727-8
Abstract: Mitochondria are double-membrane subcellular organelles with highly conserved metabolic functions including ATP production. Mitochondria shapes change continually through the combined actions of fission and fusion events rendering mitochondrial network very dynamic. Mitochondria are largely implicated… read more here.
Keywords: drp mediated; muscle degeneration; degeneration; mediated apoptosis ... See more keywords
TGF-β-driven muscle degeneration and failed regeneration underlie disease onset in a DMD mouse model.
Sign Up to like & getrecommendations! Published in 2020 at "JCI insight"
DOI: 10.1172/jci.insight.135703
Abstract: Duchenne muscular dystrophy (DMD) is a chronic muscle disease characterized by poor myogenesis and replacement of muscle by extracellular matrix. Despite the shared genetic basis, severity of these deficits varies among patients. One source of… read more here.
Keywords: muscle; disease; tgf; muscle degeneration ... See more keywords
Association between back muscle degeneration and spinal-pelvic parameters in patients with degenerative spinal kyphosis
Sign Up to like & getrecommendations! Published in 2019 at "BMC Musculoskeletal Disorders"
DOI: 10.1186/s12891-019-2837-0
Abstract: BackgroundThe paraspinal and psoas muscles have been considered to be essentially important for stabilizing the spinal column, and the muscle degeneration was found to exist in degenerative spinal kyphosis (DSK) patients. However, it is still… read more here.
Keywords: muscle; level; muscle degeneration; spinal pelvic ... See more keywords
Paraspinal Muscle Degeneration: A Potential Risk Factor for New Vertebral Compression Fractures After Percutaneous Kyphoplasty
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Interventions in Aging"
DOI: 10.2147/cia.s374857
Abstract: Background The paraspinal muscle is essential for maintaining normal spine function and structure, which degeneration is closely related to various spinal diseases. The main objective of this study was to identify the potential role of… read more here.
Keywords: muscle degeneration; muscle; risk; paraspinal muscle ... See more keywords
Sarcopenia and Back Muscle Degeneration as Risk Factors for Back Pain: A Comparative Study
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DOI: 10.31616/asj.2019.0125
Abstract: Study Design Case-control study. Purpose To investigate the independent associations of back pain with sarcopenia and with back muscle degeneration, and to introduce a new risk index for back muscle degeneration. Overview of Literature The… read more here.
Keywords: back muscle; index; back pain; muscle ... See more keywords
The association between paraspinal muscle degeneration and osteoporotic vertebral compression fracture severity in postmenopausal women
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Back and Musculoskeletal Rehabilitation"
DOI: 10.3233/bmr-220059
Abstract: BACKGROUND: According to reports in the literature, osteoporotic vertebral compression fracture (OVCF) is associated with paraspinal muscle degeneration; however, the association between the severity of OVCF and paraspinal muscle degeneration is not clear. OBJECTIVE: The… read more here.
Keywords: ovcf severity; paraspinal muscle; severity; muscle degeneration ... See more keywords