ZSF1 rat as animal model for HFpEF: Development of reduced diastolic function and skeletal muscle dysfunction
Sign Up to like & getrecommendations! Published in 2020 at "ESC Heart Failure"
DOI: 10.1002/ehf2.12915
Abstract: The prevalence of heart failure with preserved ejection fraction (HFpEF) is still increasing, and so far, no pharmaceutical treatment has proven to be effective. A key obstacle for testing new pharmaceutical substances is the availability… read more here.
Keywords: hfpef; skeletal muscle; development; muscle dysfunction ... See more keywords
Hypermethylation: Causes and Consequences in Skeletal Muscle Myopathy
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25841
Abstract: A detrimental consequence of hypermethylation is hyperhomocysteinemia (HHcy), that causes oxidative stress, inflammation, and matrix degradation, which leads to multi‐pathology in different organs. Although, it is well known that hypermethylation leads to overall gene silencing… read more here.
Keywords: skeletal muscle; hhcy; muscle; hypermethylation ... See more keywords
Glycyl‐l‐histidyl‐l‐lysine‐Cu2+ rescues cigarette smoking‐induced skeletal muscle dysfunction via a sirtuin 1‐dependent pathway
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13213
Abstract: Skeletal muscle dysfunction is an important co‐morbidity in patients with chronic obstructive pulmonary disease (COPD) and is significantly associated with increased mortality. Oxidative stress has been demonstrated an important trigger for COPD‐related skeletal muscle dysfunction.… read more here.
Keywords: skeletal muscle; muscle; glycyl histidyl; lysine ... See more keywords
Nelumbinis Stamen Ameliorates Chronic Restraint Stress-Induced Muscle Dysfunction and Fatigue in Mice by Decreasing Serum Corticosterone Levels and Activating Sestrin2.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c06318
Abstract: Nelumbo nucifera Gaertn. is an important aquatic vegetable, and its dried stamen (Nelumbinis stamen, NS) is a valuable nutraceutical usually used as a herbal tea. Here, we used ultrahigh-performance liquid chromatography (UPLC)-quadrupole time-of-flight mass spectrometry… read more here.
Keywords: stress; dysfunction fatigue; muscle dysfunction; mice ... See more keywords
Low skeletal muscle density combined with muscle dysfunction predicts adverse events after adult cardiovascular surgery
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Preventive Cardiology"
DOI: 10.1093/eurjpc/zwab061.358
Abstract: Type of funding sources: Other. Main funding source(s): This study was supported by the Grant for Japan Society for the Promotion of Science (JSPS) KAKENHI. Although muscle dysfunction is widely known as a poor prognostic… read more here.
Keywords: muscle; adverse events; skeletal muscle; muscle dysfunction ... See more keywords
Inventing the wheel: understanding heterogeneity of response to skeletal muscle dysfunction interventions in women with COPD
Sign Up to like & getrecommendations! Published in 2022 at "Thorax"
DOI: 10.1136/thorax-2022-219586
Abstract: Skeletal muscle dysfunction is arguably the most important manifestation of chronic obstructive pulmonary disease (COPD) for patients. It contributes to an inability to go about activities of daily living decreases quality of life, increases office… read more here.
Keywords: heterogeneity; women copd; skeletal muscle; muscle ... See more keywords
Cardiovasomobility: An Integrative Understanding of how Disuse Impacts Cardiovascular and Skeletal Muscle Health.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00607.2021
Abstract: Cardiovasomobility is a novel concept that encompasses the integration of cardiovascular and skeletal muscle function in health and disease with critical modification by physical activity, or lack thereof. Compelling evidence indicates that physical activity improves… read more here.
Keywords: cardiovasomobility; skeletal muscle; muscle; cardiovascular skeletal ... See more keywords
Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease. What We Know and Can Do for Our Patients
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.201710-2140ci
Abstract: &NA; Skeletal muscle dysfunction occurs in patients with chronic obstructive pulmonary disease (COPD) and affects both ventilatory and nonventilatory muscle groups. It represents a very important comorbidity that is associated with poor quality of life… read more here.
Keywords: skeletal muscle; chronic obstructive; muscle; obstructive pulmonary ... See more keywords
A comparison of muscle dysfunction in patients with chronic obstructive pulmonary disease and healthy subjects
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.congress-2018.pa709
Abstract: Background: Muscle dysfunction in COPD is associated with a poor prognosis independent of respiratory impairment, reduced survival, and high health costs. The purpose of this study was to assess and compare BMI, fat-free mass and… read more here.
Keywords: strength; muscle; copd; healthy subjects ... See more keywords
Neuromuscular electrical stimulation prevents skeletal muscle dysfunction in adjuvant-induced arthritis rat
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0179925
Abstract: Skeletal muscle weakness is a prominent feature in patients with rheumatoid arthritis (RA). In this study, we investigated whether neuromuscular electrical stimulation (NMES) training protects against skeletal muscle dysfunction in rats with adjuvant-induced arthritis (AIA).… read more here.
Keywords: skeletal muscle; muscle; stimulation; muscle dysfunction ... See more keywords
Hypercapnia-Driven Skeletal Muscle Dysfunction in an Animal Model of Pulmonary Emphysema Suggests a Complex Phenotype
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.600290
Abstract: Patients with chronic pulmonary conditions such as chronic obstructive pulmonary disease (COPD) often develop skeletal muscle dysfunction, which is strongly and independently associated with poor outcomes including higher mortality. Some of these patients also develop… read more here.
Keywords: skeletal muscle; muscle; hypercapnia; model ... See more keywords