Atrophic skeletal muscle fibre‐derived small extracellular vesicle miR‐690 inhibits satellite cell differentiation during ageing
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13106
Abstract: Sarcopenia is a common and progressive skeletal muscle disorder characterized by atrophic muscle fibres and contractile dysfunction. Accumulating evidence shows that the number and function of satellite cells (SCs) decline and become impaired during ageing,… read more here.
Keywords: muscle; satellite cell; muscle fibres; atrophic skeletal ... See more keywords
Decoding mitochondrial heterogeneity in single muscle fibres by imaging mass cytometry
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-70885-3
Abstract: The study of skeletal muscle continues to support the accurate diagnosis of mitochondrial disease and remains important in delineating molecular disease mechanisms. The heterogeneous expression of oxidative phosphorylation proteins and resulting respiratory deficiency are both… read more here.
Keywords: mass cytometry; muscle; imaging mass; single muscle ... See more keywords
Measurements of basal d‐glucose transport through GLUT1 across the intact plasma membrane of isolated segments from single fast‐ and slow‐twitch skeletal muscle fibres of rat
Sign Up to like & getrecommendations! Published in 2022 at "Acta Physiologica"
DOI: 10.1111/apha.13789
Abstract: To develop a method for direct measurement of the fluorescent d‐glucose analogue 2‐NBDG transport across the plasma membrane of single skeletal muscle fibres and derive the theoretical framework for determining the kinetic parameters for d‐glucose… read more here.
Keywords: skeletal muscle; muscle fibres; plasma membrane; glucose transport ... See more keywords
There and back again: 50 years of wandering through terra incognita fusorum.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental physiology"
DOI: 10.1113/ep090760
Abstract: NEW FINDINGS What is the topic of this paper? This paper concerns the relationship between structure and function of the mammalian muscle spindle, its intrafusal muscle fibres and their sensory and motor innervation. What advances… read more here.
Keywords: back years; years wandering; muscle; muscle fibres ... See more keywords
Heme-Induced Oxidation of Cysteine Groups of Myofilament Proteins Leads to Contractile Dysfunction of Permeabilized Human Skeletal Muscle Fibres
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21218172
Abstract: Heme released from red blood cells targets a number of cell components including the cytoskeleton. The purpose of the present study was to determine the impact of free heme (20–300 µM) on human skeletal muscle… read more here.
Keywords: skeletal muscle; oxidation; heme; muscle ... See more keywords
High-Intensity Training Represses FXYD5 and Glycosylates Na,K-ATPase in Type II Muscle Fibres, Which Are Linked with Improved Muscle K+ Handling and Performance
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065587
Abstract: Na+/K+ ATPase (NKA) comprises several subunits to provide isozyme heterogeneity in a tissue-specific manner. An abundance of NKA α, β, and FXYD1 subunits is well-described in human skeletal muscle, but not much is known about… read more here.
Keywords: fxyd5 abundance; training; muscle; high intensity ... See more keywords