Genes controlling skeletal muscle glucose uptake and their regulation by endurance and resistance exercise.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30179
Abstract: Exercise improves the insulin sensitivity of glucose uptake in skeletal muscle. Due to that, exercise has become a cornerstone treatment for type 2 diabetes mellitus (T2DM). The mechanisms by which exercise improves skeletal muscle insulin sensitivity… read more here.
Keywords: skeletal muscle; muscle; glucose uptake; insulin sensitivity ... See more keywords
Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15963-w
Abstract: Crosstalk between liver and skeletal muscle is vital for glucose homeostasis. Hepatokines, liver-derived proteins that play an important role in regulating muscle metabolism, are important to this communication. Here we identify apolipoprotein J (ApoJ) as… read more here.
Keywords: insulin; metabolism insulin; muscle; glucose metabolism ... See more keywords
Kolaviron modulates dysregulated metabolism in oxidative pancreatic injury and inhibits intestinal glucose absorption with concomitant stimulation of muscle glucose uptake.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of physiology and biochemistry"
DOI: 10.1080/13813455.2020.1806331
Abstract: This present study investigated the antioxidative and antidiabetic properties of kolaviron by analysing its inhibitory effect on key metabolic activities linked to T2D, in vitro and ex vivo. Kolaviron significantly inhibited α-glucosidase and α-amylase activities, and… read more here.
Keywords: metabolism; glucose uptake; glucose absorption; kolaviron ... See more keywords
Gene deletion of γ‐actin impairs insulin‐stimulated skeletal muscle glucose uptake in growing mice but not in mature adult mice
Sign Up to like & getrecommendations! Published in 2022 at "Physiological Reports"
DOI: 10.14814/phy2.15183
Abstract: The cortical cytoskeleton, consisting of the cytoplasmic actin isoforms β and/or γ‐actin, has been implicated in insulin‐stimulated GLUT4 translocation and glucose uptake in muscle and adipose cell culture. Furthermore, transgenic inhibition of multiple actin‐regulating proteins… read more here.
Keywords: insulin stimulated; glucose uptake; muscle glucose; mice ... See more keywords
AMPK and TBC1D1 Regulate Muscle Glucose Uptake After, but Not During, Exercise and Contraction
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DOI: 10.2337/db19-0050
Abstract: Exercise increases glucose uptake in skeletal muscle independently of insulin signaling. This makes exercise an effective stimulus to increase glucose uptake in insulin-resistant skeletal muscle. AMPK has been suggested to regulate muscle glucose uptake during… read more here.
Keywords: muscle; glucose uptake; contraction; muscle glucose ... See more keywords
Recombinant Uncarboxylated Osteocalcin Per Se Enhances Mouse Skeletal Muscle Glucose Uptake in both Extensor Digitorum Longus and Soleus Muscles
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2017.00330
Abstract: Emerging evidence suggests that undercarboxylated osteocalcin (ucOC) improves muscle glucose uptake in rodents. However, whether ucOC can directly increase glucose uptake in both glycolytic and oxidative muscles and the possible mechanisms of action still need… read more here.
Keywords: muscle glucose; soleus muscles; phosphorylation; glucose uptake ... See more keywords
Regulation of Skeletal Muscle Glucose Transport and Glucose Metabolism by Exercise Training
Sign Up to like & getrecommendations! Published in 2019 at "Nutrients"
DOI: 10.3390/nu11102432
Abstract: Aerobic exercise training and resistance exercise training are both well-known for their ability to improve human health; especially in individuals with type 2 diabetes. However, there are critical differences between these two main forms of… read more here.
Keywords: muscle glucose; skeletal muscle; exercise; exercise training ... See more keywords