Metabolic and molecular changes associated with the increased skeletal muscle insulin action 24-48 h after exercise in young and old humans.
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DOI: 10.1042/bst20170198
Abstract: The molecular and metabolic mechanisms underlying the increase in insulin sensitivity (i.e. increased insulin-stimulated skeletal muscle glucose uptake, phosphorylation and storage as glycogen) observed from 12 to 48 h following a single bout of exercise in… read more here.
Keywords: skeletal muscle; insulin; molecular changes; muscle ... See more keywords
Comment on “Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women”
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DOI: 10.1126/science.abj1696
Abstract: Yoshino et al. (Reports, 11 June 2021, p. 1224) have reported that nicotinamide mononucleotide (NMN) increases muscle insulin sensitivity in prediabetic women. However, the 13 women who received NMN had hepatic lipid content of 6.3… read more here.
Keywords: nicotinamide mononucleotide; increases muscle; sensitivity prediabetic; prediabetic women ... See more keywords
Downregulation of ALDH6A1 is a New Marker of Muscle Insulin Resistance in Type 2 Diabetes Mellitus
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DOI: 10.2147/ijgm.s343727
Abstract: Purpose Skeletal muscle insulin resistance (IR) is an important etiology of type 2 diabetes mellitus (T2DM); however, its molecular mechanism is yet to be fully defined. This study attempted to identify the gene expression patterns… read more here.
Keywords: expression; muscle; muscle insulin; type diabetes ... See more keywords
Calorie Restriction-Induced Increase in Skeletal Muscle Insulin Sensitivity Is Not Prevented by Overexpression of the p55α Subunit of Phosphoinositide 3-Kinase
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DOI: 10.3389/fphys.2018.00789
Abstract: Introduction: The Phosphoinositide 3-kinase (PI3K) signaling pathway plays an important role in skeletal muscle insulin-stimulated glucose uptake. While whole-body and tissue specific knockout (KO) of individual or combinations of the regulatory subunits of PI3K (p85α,… read more here.
Keywords: skeletal muscle; muscle; overexpression p55; muscle insulin ... See more keywords