Weight and skeletal muscle loss with cabozantinib in metastatic renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13021
Abstract: Cabozantinib, a standard of care metastatic renal cell carcinoma (mRCC), may be associated with weight and muscle loss. These effects of new generation VEGFR tyrosine kinase inhibitor on muscle mass loss are poorly described. read more here.
Keywords: cell carcinoma; renal cell; metastatic renal; loss ... See more keywords
Skeletal muscle loss phenotype in cirrhosis: A nationwide analysis of hospitalized patients.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical nutrition"
DOI: 10.1016/j.clnu.2020.03.032
Abstract: BACKGROUND & AIMS There are very limited data on the healthcare burden of muscle loss, the most frequent complication in hospitalized cirrhotics. We determined the healthcare impact of a muscle loss phenotype in hospitalized cirrhotics.… read more here.
Keywords: loss phenotype; loss; cirrhosis; muscle loss ... See more keywords
Targeting intramuscular adipose tissue expansion to preserve contractile function in volumetric muscle loss: A potentially novel therapy?
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2021.03.006
Abstract: In volumetric muscle loss (VML), the severity of trauma exceeds a muscle's regenerative capacity. VML causes permanent functional impairments for which there are no rehabilitative, pharmacological, or regenerative medicine interventions. Driving failed regeneration in VML… read more here.
Keywords: intramuscular adipose; muscle; tissue; volumetric muscle ... See more keywords
Screening for muscle loss in patients established on peritoneal dialysis using bioimpedance
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Clinical Nutrition"
DOI: 10.1038/ejcn.2016.202
Abstract: Background/objectivesKidney dialysis patients with sarcopenia have increased mortality. Screening for low muscle mass may allow interventions at an earlier stage to help improve outcomes. We wished to determine the prevalence of low muscle mass in… read more here.
Keywords: muscle; mass; peritoneal dialysis; loss patients ... See more keywords
Pre-innervated tissue-engineered muscle promotes a pro-regenerative microenvironment following volumetric muscle loss
Sign Up to like & getrecommendations! Published in 2020 at "Communications Biology"
DOI: 10.1038/s42003-020-1056-4
Abstract: Volumetric muscle loss (VML) is the traumatic or surgical loss of skeletal muscle beyond the inherent regenerative capacity of the body, generally leading to severe functional deficit. Formation of appropriate somato-motor innervations remains one of… read more here.
Keywords: muscle; volumetric muscle; engineered muscle; tissue engineered ... See more keywords
Spatiotemporal mapping of immune and stem cell dysregulation after volumetric muscle loss
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1101/2022.06.03.494707
Abstract: Volumetric muscle loss (VML) is an acute trauma that results in persistent inflammation, supplantation of muscle tissue with fibrotic scarring, and decreased muscle function. The cell types, nature of cellular communication and tissue locations that… read more here.
Keywords: cell; stem cell; volumetric muscle; muscle ... See more keywords
Appendicular lean mass and site‐specific muscle loss in the extremities correlate with dynamic strength
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Physiology and Functional Imaging"
DOI: 10.1111/cpf.12292
Abstract: Previous studies have reported the non‐homogenous loss of muscle mass (site‐specific muscle loss) with ageing, but this relationship to the loss of strength is not totally understood. read more here.
Keywords: muscle loss; site specific; muscle; mass site ... See more keywords
Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00811.2018
Abstract: Short-term muscle disuse induces significant muscle loss in older adults and in some reports may be more accelerated with aging. Identifying muscle transcriptional events in response to bed rest may help identify therapeutic targets to… read more here.
Keywords: skeletal muscle; bed rest; muscle; response bed ... See more keywords
Preferred M2 Polarization by ASC-Based Hydrogel Accelerated Angiogenesis and Myogenesis in Volumetric Muscle Loss Rats
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cells International"
DOI: 10.1155/2017/2896874
Abstract: Volumetric muscle loss (VML) injury resulted from massive muscle defects and diseases for which there are still no effective therapeutic treatments. This study aimed to investigate the effects of rat adipose-derived mesenchymal stem cells (rASCs)… read more here.
Keywords: based hydrogel; angiogenesis; muscle; myogenesis ... See more keywords
Skeletal muscle loss under chemotherapy and its association with survival and systemic treatment toxicity in metastatic colorectal cancer: An AGEO prospective multicenter study.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.4025
Abstract: 4025Background: We showed in a previous work that “Patient Generated-Subjective Global Assessment” (PG-SGA) was independently associated with survival and treatment toxicities in non-pretreated met... read more here.
Keywords: skeletal muscle; loss chemotherapy; chemotherapy association; association survival ... See more keywords
Perioperative Ghrelin Administration Attenuates Postoperative Skeletal Muscle Loss in Patients Undergoing Esophagectomy for Esophageal Cancer: Secondary Analysis of a Randomized Controlled Trial
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-022-11436-0
Abstract: Ghrelin has been reported to reduce postoperative weight loss by improving appetite and food intake in patients undergoing upper gastrointestinal surgery. We aimed to investigate whether growth hormone induction, another essential effect of ghrelin, may… read more here.
Keywords: esophageal cancer; muscle; ghrelin; loss ... See more keywords