Curcumin: An effective adjunct in patients with statin‐associated muscle symptoms?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12140
Abstract: In spite of the unequivocal efficacy of statins in reducing primary and secondary cardiovascular events, the use of these drugs in a considerable number of patients is limited because of statin intolerance, mainly statin‐associated muscle… read more here.
Keywords: curcumin effective; muscle; statin associated; associated muscle ... See more keywords
Statin-associated myopathy and the quest for biomarkers: can we effectively predict statin-associated muscle symptoms?
Sign Up to like & getrecommendations! Published in 2017 at "Drug discovery today"
DOI: 10.1016/j.drudis.2016.09.001
Abstract: Over the past three decades, statins have become the cornerstone of prevention and treatment of atherosclerotic cardiovascular and metabolic diseases. Albeit generally well tolerated, these drugs can elicit a variety of muscle-associated symptoms that represent… read more here.
Keywords: myopathy quest; muscle; statin associated; associated myopathy ... See more keywords
Statin-associated muscle symptoms-Managing the highly intolerant.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of clinical lipidology"
DOI: 10.1016/j.jacl.2017.01.006
Abstract: Musculoskeletal symptoms are the most commonly reported adverse effects associated with statin therapy. Yet, certain data indicate that these symptoms often present in populations with underlying musculoskeletal complaints and are not likely statin related. Switching… read more here.
Keywords: muscle; statin associated; associated muscle; highly intolerant ... See more keywords
Statin-associated muscle symptoms: beware of the nocebo effect
Sign Up to like & getrecommendations! Published in 2017 at "The Lancet"
DOI: 10.1016/s0140-6736(17)31163-7
Abstract: Full Text Tables and Figures References Patient-reported statin intolerance, predominantly due to statin-associated muscle symptoms (SAMS), is a common and difficult-to-manage condition affecting millions of patients worldwide. Different expert panels have proposed various definitions and… read more here.
Keywords: statin intolerance; statin associated; associated muscle; statin ... See more keywords
Effects of Vitamin D Supplementation in Patients with Statin-Associated Muscle Symptoms and Low Vitamin D Levels.
Sign Up to like & getrecommendations! Published in 2022 at "Metabolic syndrome and related disorders"
DOI: 10.1089/met.2021.0127
Abstract: Background: Statin therapy is a cornerstone of cardiovascular disease treatment and prevention. Unfortunately, 7%-29% of statin-treated patients complain of muscular fatigue, cramps, and/or pain (statin-associated muscle symptoms [SAMS]). In recent years, the important role of… read more here.
Keywords: vitamin levels; statin associated; associated muscle; muscle ... See more keywords
Coenzyme Q10 as Treatment for Statin-Associated Muscle Symptoms-A Good Idea, but….
Sign Up to like & getrecommendations! Published in 2018 at "Advances in nutrition"
DOI: 10.1093/advances/nmy010
Abstract: 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) are extremely well tolerated but are associated with a range of mild-to-moderate statin-associated muscle symptoms (SAMS). Estimates of SAMS incidence vary from read more here.
Keywords: statin associated; treatment; associated muscle; coenzyme ... See more keywords
P134 Normal creatine kinase in inflammatory myositis
Sign Up to like & getrecommendations! Published in 2025 at "Rheumatology"
DOI: 10.1093/rheumatology/keaf142.174
Abstract: Inflammatory myositis presents variably, not necessarily with muscle symptoms. Diagnosis can be challenging, potentially helped by biochemical and immunological tests, neurophysiology and imaging. A normal creatine kinase (CK) may dissuade clinicians from considering myositis; however,… read more here.
Keywords: rheumatology; myositis; inflammatory myositis; muscle symptoms ... See more keywords
Statin‐associated muscle symptoms: A comprehensive exploration of epidemiology, pathophysiology, diagnosis, and clinical management strategies
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.15337
Abstract: Statins are the first line of treatment for both primary and secondary prevention of atherosclerotic cardiovascular disease. Despite the positive effects of statins on cardiovascular events, not all patients can use them at an optimized… read more here.
Keywords: epidemiology; associated muscle; muscle; muscle symptoms ... See more keywords
Coenzyme Q10 supplementation for the treatment of statin-associated muscle symptoms.
Sign Up to like & getrecommendations! Published in 2022 at "Future cardiology"
DOI: 10.2217/fca-2021-0106
Abstract: Aim: To determine the association of coenzyme Q10 (CoQ10) use with the resolution of statin-associated muscle symptoms (SAMS). Patients & methods: Retrospective analysis of a large, multi-center survey study of SAMS (total n = 511; n = 64 CoQ10… read more here.
Keywords: coq10; statin associated; associated muscle; coenzyme q10 ... See more keywords
PCSK9 inhibitors and inclisiran with or without statin therapy on incident muscle symptoms and creatine kinase: a systematic review and network meta-analysis
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2024.1375040
Abstract: Background Atherosclerotic cardiovascular disease (ASCVD), a leading cause of global fatalities, has inconsistent findings regarding the impact of muscle symptoms despite promising clinical trials involving PCSK9 inhibitors (PCSK9i) and siRNA as potential therapeutic options. Methods… read more here.
Keywords: review; muscle; analysis; muscle symptoms ... See more keywords
Impact of X-Linked Hypophosphatemia on Muscle Symptoms
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13122415
Abstract: X-linked hypophosphatemia (XLH) is the most common hereditary form of rickets and deficiency of renal tubular phosphate transport in humans. XLH is caused by the inactivation of mutations within the phosphate-regulating endopeptidase homolog X-linked (PHEX)… read more here.
Keywords: phosphate; muscle; impact linked; hypophosphatemia muscle ... See more keywords