Skeletal muscle wasting in chronic heart failure
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DOI: 10.1002/ehf2.12387
Abstract: Patients suffering from chronic heart failure (CHF) show an increased prevalence (~20% in elderly CHF patients) of loss of muscle mass and muscle function (i.e. sarcopenia) compared with healthy elderly people. Sarcopenia, which can also… read more here.
Keywords: muscle; chronic heart; muscle wasting; heart failure ... See more keywords
Independent link between peripheral artery disease and muscle wasting in patients with heart failure
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DOI: 10.1002/ehf2.12951
Abstract: A high prevalence of muscle wasting, that is, reduction in muscle mass, in patients with peripheral artery disease (PAD) and heart failure (HF) has been reported. However, whether the association between PAD and muscle wasting… read more here.
Keywords: muscle; peripheral artery; muscle wasting; heart failure ... See more keywords
Indoprofen prevents muscle wasting in aged mice through activation of PDK1/AKT pathway
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12558
Abstract: Abstract Background Muscle wasting, resulting from aging or pathological conditions, leads to reduced quality of life, increased morbidity, and increased mortality. Much research effort has been focused on the development of exercise mimetics to prevent… read more here.
Keywords: indoprofen; muscle; activation pdk1; muscle wasting ... See more keywords
Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia
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DOI: 10.1002/jcsm.12561
Abstract: Abstract Background Cachexia, a multifactorial syndrome affecting more than 50% of patients with advanced cancer and responsible for ~20% of cancer‐associated deaths, is still a poorly understood process without a standard cure available. Skeletal muscle… read more here.
Keywords: muscle; muscle wasting; rage; cancer cachexia ... See more keywords
Cachectic muscle wasting in acute myeloid leukaemia: a sleeping giant with dire clinical consequences
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DOI: 10.1002/jcsm.12880
Abstract: Acute myeloid leukaemia (AML) is a haematological malignancy with poor survival odds, particularly in the older (>65 years) population, in whom it is most prevalent. Treatment consists of induction and consolidation chemotherapy to remit the… read more here.
Keywords: muscle; acute myeloid; muscle wasting; myeloid leukaemia ... See more keywords
Ginsenoside Rd ameliorates muscle wasting by suppressing the signal transducer and activator of transcription 3 pathway
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DOI: 10.1002/jcsm.13084
Abstract: The effects of some drugs, aging, cancers, and other diseases can cause muscle wasting. Currently, there are no effective drugs for treating muscle wasting. In this study, the effects of ginsenoside Rd (GRd) on muscle… read more here.
Keywords: muscle wasting; ameliorates muscle; muscle; ginsenoside ameliorates ... See more keywords
Cellular interplay in skeletal muscle regeneration and wasting: insights from animal models
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DOI: 10.1002/jcsm.13103
Abstract: Skeletal muscle wasting, whether related to physiological ageing, muscle disuse or to an underlying chronic disease, is a key determinant to quality of life and mortality. However, cellular basis responsible for increased catabolism in myocytes… read more here.
Keywords: muscle wasting; animal models; disease; muscle ... See more keywords
The impact of senescence on muscle wasting in chronic kidney disease
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DOI: 10.1002/jcsm.13112
Abstract: Muscle wasting is a common complication of chronic kidney disease (CKD) that is associated with higher mortality. Although the mechanisms of myofibre loss in CKD has been widely studied, the contribution of muscle precursor cell… read more here.
Keywords: muscle wasting; chronic kidney; muscle; senescence ... See more keywords
Molecular mechanisms of post‐burn muscle wasting and the therapeutic potential of physical exercise
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DOI: 10.1002/jcsm.13188
Abstract: After a severe burn injury, a systemic stress response activates metabolic and inflammatory derangements that, among other, leads to muscle mass loss (muscle wasting). These negative effects on skeletal muscle continue for several months or… read more here.
Keywords: muscle wasting; molecular mechanisms; muscle; post burn ... See more keywords
C‐terminal agrin fragment as a biomarker of muscle wasting and weakness: a narrative review
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DOI: 10.1002/jcsm.13189
Abstract: Ageing is accompanied by an inexorable loss of muscle mass and functionality and represents a major risk factor for numerous diseases such as cancer, diabetes and cardiovascular and pulmonary diseases. This progressive loss of muscle… read more here.
Keywords: caf; muscle wasting; biomarker; muscle ... See more keywords
Preventing muscle wasting: pro‐insulin C‐peptide prevents loss in muscle mass in streptozotocin‐diabetic rats
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DOI: 10.1002/jcsm.13210
Abstract: C‐peptide therapy exerts several positive actions on nerves, vasculature, smooth muscle relaxation, kidney function and bone. To date, the role of C‐peptide in preventing type 1 diabetes‐related muscle atrophy has not been investigated. Our aim… read more here.
Keywords: diabetic rats; preventing muscle; muscle wasting; wasting pro ... See more keywords