Dysfunctional sarcomere contractility contributes to muscle weakness in ACTA1‐related nemaline myopathy (NEM3)
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Neurology"
DOI: 10.1002/ana.25144
Abstract: Nemaline myopathy (NM) is one of the most common congenital nondystrophic myopathies and is characterized by muscle weakness, often from birth. Mutations in ACTA1 are a frequent cause of NM (ie, NEM3). ACTA1 encodes alpha‐actin… read more here.
Keywords: contributes muscle; muscle weakness; acta1; weakness ... See more keywords
Etiopathophysiological role of the renin–angiotensin–aldosterone system in age‐related muscular weakening: RAAS‐independent beneficial role of ACE2 in muscle weakness
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23030
Abstract: Aging is accompanied by major changes in body composition that can negatively affect functional status in older adults, including a progressive decrease in muscle mass, strength, and quality. The prevalence of sarcopenia has varied considerably,… read more here.
Keywords: system; role; muscle; muscle weakness ... See more keywords
Fast skeletal muscle troponin activator CK‐2066260 mitigates skeletal muscle weakness independently of the underlying cause
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12624
Abstract: Muscle weakness is a common symptom in numerous diseases and a regularly occurring problem associated with ageing. Prolonged low‐frequency force depression (PLFFD) is a form of exercise‐induced skeletal muscle weakness observed after exercise. Three different… read more here.
Keywords: skeletal muscle; fast skeletal; muscle; muscle weakness ... See more keywords
Obesity attenuates inflammation, protein catabolism, dyslipidaemia, and muscle weakness during sepsis, independent of leptin
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DOI: 10.1002/jcsm.12904
Abstract: Muscle weakness is a frequently occurring complication of sepsis, associated with increased morbidity and mortality. Interestingly, obesity attenuates sepsis‐induced muscle wasting and weakness. As the adipokine leptin is strongly elevated in obesity and has been… read more here.
Keywords: sepsis; obesity attenuates; muscle weakness; muscle ... See more keywords
Exercise reduces intramuscular stress and counteracts muscle weakness in mice with breast cancer.
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DOI: 10.1002/jcsm.12944
Abstract: BACKGROUND Patients with breast cancer exhibit muscle weakness, which is associated with increased mortality risk and reduced quality of life. Muscle weakness is experienced even in the absence of loss of muscle mass in breast… read more here.
Keywords: cancer; muscle; breast cancer; exercise ... See more keywords
Variability in Disease Severity in Siblings With Homozygous Missense Variant of ADSSL1: Clinical Genetic Study and Review of Literatures
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DOI: 10.1002/mgg3.70041
Abstract: Distal myopathies are genetic muscle disorders caused by mutations in various genes. A study found that mutations in adenylosuccinate synthetase‐like 1 (ADSSL1) are associated with distal myopathy in nine patients from six unrelated families in… read more here.
Keywords: disease severity; muscle; muscle weakness; variability disease ... See more keywords
SOD1-related inherited peripheral neuropathies in a Japanese cohort: genetic variants and clinical insights
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DOI: 10.1007/s00415-025-12925-4
Abstract: Inherited peripheral neuropathies (IPNs) encompass a wide range of disorders affecting the peripheral nervous system, often with complex genetic causes and frequent underdiagnosis. The variants in the superoxide dismutase 1 (SOD1) gene, primarily linked to… read more here.
Keywords: variants clinical; muscle weakness; sod1; inherited peripheral ... See more keywords
Recurrent Muscle Cramps in a Boy
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DOI: 10.1007/s12098-021-03939-7
Abstract: To the Editor: Andersen–Tawil syndrome (ATS) is a clinical entity characterized by a classic triad of episodic flaccid muscle weakness (periodic paralysis), ventricular arrhythmia with prolonged QT interval, and skeletal anomalies [1]. It may occur… read more here.
Keywords: muscle; muscle weakness; muscle cramps; recurrent muscle ... See more keywords
Eteplirsen Treatment for Duchenne Muscular Dystrophy: A Qualitative Patient Experience Study
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DOI: 10.1007/s12325-024-02915-9
Abstract: Duchenne muscular dystrophy (DMD) is characterized by rapid functional decline. Current available treatment options aim to delay disease progression or stabilize physical function. To aid in healthcare providers’ understanding of the symptoms of disease that… read more here.
Keywords: duchenne muscular; treatment; muscle weakness; weakness ... See more keywords
Habitual dietary fat intake and risk of muscle weakness and lower-extremity functional impairment in older adults: A prospective cohort study.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical nutrition"
DOI: 10.1016/j.clnu.2020.03.018
Abstract: BACKGROUND & AIMS Fatty acid supplementation increases muscle mass and function in older adults, but the effect of habitual dietary intake is uncertain. Therefore, the objective of this study was to examine the association between… read more here.
Keywords: muscle weakness; risk; risk muscle; intake ... See more keywords
Biomechanical consequences of running with deep core muscle weakness.
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DOI: 10.1016/j.jbiomech.2017.11.037
Abstract: The deep core muscles are often neglected or improperly trained in athletes. Improper function of this musculature may lead to abnormal spinal loading, muscle strain, or injury to spinal structures, all of which have been… read more here.
Keywords: deep core; muscle weakness; core muscle; core ... See more keywords