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Published in 2017 at "Drug testing and analysis"
DOI: 10.1002/dta.2293
Abstract: Musk, the dried secretion of the musk pod (sac) of adult male musk deer, has been used as traditional Chinese Medicine (TCM) in China and south-east Asian countries for thousands of years. Due to the…
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Keywords:
administration;
doping control;
administration doping;
musk administration ... See more keywords
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Published in 2021 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2021.04.019
Abstract: OBJECTIVE Patients with myasthenia gravis associated with muscle-specific tyrosine kinase antibodies (MuSK-MG) often manifest signs of cholinergic hyperactivity with standard doses of acetylcholinesterase inhibitors (AChE-Is). Aim of the study was to investigate whether repetitive compound…
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Keywords:
cholinergic hyperactivity;
hyperactivity;
study;
myasthenia gravis ... See more keywords
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Published in 2017 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2017.08.006
Abstract: Since the first report of experimental animal models of myasthenia gravis (MG) with autoantibodies against low-density lipoprotein receptor-related protein 4 (LRP4), there have not been any major reports replicating the pathogenicity of anti-LRP4 antibodies (Abs).…
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Keywords:
immunization;
myasthenia gravis;
mice;
lrp4 ... See more keywords
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Published in 2020 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2020.116690
Abstract: BACKGROUND B-cell targeted therapy with rituximab has shown durable response in treating refractory myasthenia gravis (MG). This study compares the response to rituximab between patients with acetylcholine receptor autoantibody positive (AChR+) and muscle-specific kinase autoantibody…
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Keywords:
rituximab;
achr;
response;
study ... See more keywords
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Published in 2019 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2018.12.002
Abstract: Amyotrophic lateral sclerosis (ALS), a neurodegenerative disease affecting motor neurons, is characterized by rapid decline of motor function and ultimately respiratory failure. As motor neuron death occurs late in the disease, therapeutics that prevent the…
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Keywords:
musk activation;
benefit;
kinase;
functional benefit ... See more keywords
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Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.10.017
Abstract: The role of agrin, Lrp4 and MuSK, key organizers of neuromuscular synaptogenesis, in the developing CNS is only poorly understood. We investigated the role of these proteins in cultured mouse embryonic cortical neurons from wildtype…
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Keywords:
synaptogenesis;
puncta;
lrp4 musk;
agrin lrp4 ... See more keywords
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Published in 2018 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.13543
Abstract: Myasthenia gravis (MG) with antibodies to muscle‐specific kinase (MuSK) is characterized by fluctuating fatigable weakness. In MuSK MG, involvement of bulbar muscles, neck, and shoulder and respiratory weakness are more prominent than in acetylcholine receptor…
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Keywords:
specific kinase;
passive transfer;
myasthenia gravis;
muscle specific ... See more keywords
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Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02269-21
Abstract: Forest musk deer is listed as an endangered species by International Union for Conservation of Nature Red List, and the Chinese government has introduced captivity breeding measures to curb the rapid decline of the musk…
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Keywords:
colonization;
blastocystis;
forest musk;
musk ... See more keywords
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Published in 2017 at "Laboratory Animals"
DOI: 10.1177/0023677217695851
Abstract: Several cancer chemotherapies cause nausea and vomiting, which can be dose-limiting. Musk shrews are used as preclinical models for chemotherapy-induced emesis and for antiemetic effectiveness. Unlike rats and mice, shrews possess a vomiting reflex and…
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Keywords:
body surface;
surface area;
chemotherapy induced;
musk ... See more keywords
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Published in 2020 at "BMC Neurology"
DOI: 10.1186/s12883-020-01813-1
Abstract: Background The onset of myasthenia (MG) gravis with anti-muscle-specific tyrosine kinase (MuSK) antibodies most commonly peaks in the fourth decade of life, and MG with MuSK antibodies (MuSK-MG) rarely coexists with a malignant tumor. To…
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Keywords:
anti muscle;
gravis anti;
case;
myasthenia gravis ... See more keywords
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Published in 2021 at "Critical reviews in eukaryotic gene expression"
DOI: 10.1615/critreveukaryotgeneexpr.2021037369
Abstract: To determine if differential profile of miRNAs in peripheral blood mononuclear cells (PBMCs) could be identified in muscle-specific receptor tyrosine kinase antibody positive myasthenia gravis (MuSK-MG) and linked to disease stage, a case-control method was…
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Keywords:
expression;
blood mononuclear;
myasthenia gravis;
mononuclear cells ... See more keywords