Steroid profile and IRMS analysis of musk administration for doping control.
Sign Up to like & getrecommendations! Published in 2017 at "Drug testing and analysis"
DOI: 10.1002/dta.2293
Abstract: Musk, the dried secretion of the musk pod (sac) of adult male musk deer, has been used as traditional Chinese Medicine (TCM) in China and south-east Asian countries for thousands of years. Due to the… read more here.
Keywords: administration; doping control; administration doping; musk administration ... See more keywords
Cholinergic hyperactivity in patients with myasthenia gravis with MuSK antibodies: A neurophysiological study
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2021.04.019
Abstract: OBJECTIVE Patients with myasthenia gravis associated with muscle-specific tyrosine kinase antibodies (MuSK-MG) often manifest signs of cholinergic hyperactivity with standard doses of acetylcholinesterase inhibitors (AChE-Is). Aim of the study was to investigate whether repetitive compound… read more here.
Keywords: cholinergic hyperactivity; hyperactivity; study; myasthenia gravis ... See more keywords
Immunization of mice with LRP4 induces myasthenia similar to MuSK-associated myasthenia gravis
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2017.08.006
Abstract: Since the first report of experimental animal models of myasthenia gravis (MG) with autoantibodies against low-density lipoprotein receptor-related protein 4 (LRP4), there have not been any major reports replicating the pathogenicity of anti-LRP4 antibodies (Abs).… read more here.
Keywords: immunization; myasthenia gravis; mice; lrp4 ... See more keywords
Differential response to rituximab in anti-AChR and anti-MuSK positive myasthenia gravis patients: a single-center retrospective study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2020.116690
Abstract: BACKGROUND B-cell targeted therapy with rituximab has shown durable response in treating refractory myasthenia gravis (MG). This study compares the response to rituximab between patients with acetylcholine receptor autoantibody positive (AChR+) and muscle-specific kinase autoantibody… read more here.
Keywords: rituximab; achr; response; study ... See more keywords
Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS
Sign Up to like & getrecommendations! Published in 2019 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2018.12.002
Abstract: Amyotrophic lateral sclerosis (ALS), a neurodegenerative disease affecting motor neurons, is characterized by rapid decline of motor function and ultimately respiratory failure. As motor neuron death occurs late in the disease, therapeutics that prevent the… read more here.
Keywords: musk activation; benefit; kinase; functional benefit ... See more keywords
The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.10.017
Abstract: The role of agrin, Lrp4 and MuSK, key organizers of neuromuscular synaptogenesis, in the developing CNS is only poorly understood. We investigated the role of these proteins in cultured mouse embryonic cortical neurons from wildtype… read more here.
Keywords: synaptogenesis; puncta; lrp4 musk; agrin lrp4 ... See more keywords
Passive transfer models of myasthenia gravis with muscle‐specific kinase antibodies
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.13543
Abstract: Myasthenia gravis (MG) with antibodies to muscle‐specific kinase (MuSK) is characterized by fluctuating fatigable weakness. In MuSK MG, involvement of bulbar muscles, neck, and shoulder and respiratory weakness are more prominent than in acetylcholine receptor… read more here.
Keywords: specific kinase; passive transfer; myasthenia gravis; muscle specific ... See more keywords
Changes in Gut Microbiota Composition Associated with the Presence of Enteric Protist Blastocystis in Captive Forest Musk Deer (Moschus Berezovskii)
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02269-21
Abstract: Forest musk deer is listed as an endangered species by International Union for Conservation of Nature Red List, and the Chinese government has introduced captivity breeding measures to curb the rapid decline of the musk… read more here.
Keywords: colonization; blastocystis; forest musk; musk ... See more keywords
Estimation of body surface area in the musk shrew (Suncus murinus): a small animal for testing chemotherapy-induced emesis
Sign Up to like & getrecommendations! Published in 2017 at "Laboratory Animals"
DOI: 10.1177/0023677217695851
Abstract: Several cancer chemotherapies cause nausea and vomiting, which can be dose-limiting. Musk shrews are used as preclinical models for chemotherapy-induced emesis and for antiemetic effectiveness. Unlike rats and mice, shrews possess a vomiting reflex and… read more here.
Keywords: body surface; surface area; chemotherapy induced; musk ... See more keywords
Myasthenia gravis with anti-muscle-specific tyrosine kinase antibodies during therapy for multiple myeloma: a case report
Sign Up to like & getrecommendations! Published in 2020 at "BMC Neurology"
DOI: 10.1186/s12883-020-01813-1
Abstract: Background The onset of myasthenia (MG) gravis with anti-muscle-specific tyrosine kinase (MuSK) antibodies most commonly peaks in the fourth decade of life, and MG with MuSK antibodies (MuSK-MG) rarely coexists with a malignant tumor. To… read more here.
Keywords: anti muscle; gravis anti; case; myasthenia gravis ... See more keywords
Differential Expression of miRNA in the Peripheral Blood Mononuclear Cells in Myasthenia Gravis with Muscle-Specific Receptor Tyrosine Kinase Antibodies.
Sign Up to like & getrecommendations! Published in 2021 at "Critical reviews in eukaryotic gene expression"
DOI: 10.1615/critreveukaryotgeneexpr.2021037369
Abstract: To determine if differential profile of miRNAs in peripheral blood mononuclear cells (PBMCs) could be identified in muscle-specific receptor tyrosine kinase antibody positive myasthenia gravis (MuSK-MG) and linked to disease stage, a case-control method was… read more here.
Keywords: expression; blood mononuclear; myasthenia gravis; mononuclear cells ... See more keywords