Multihit TP53 Mutations in Myeloproliferative Neoplasms and Acute Myeloid Leukemia: Comparative Analysis of Survival and Risk Factors in 142 Informative Cases
Sign Up to like & getrecommendations! Published in 2025 at "American Journal of Hematology"
DOI: 10.1002/ajh.27670
Abstract: A total of 142 patients with myeloproliferative neoplasms (MPNs) or acute myeloid leukemia (AML) associated with multihit TP53 mutations (mTP53 MUT) were accessed from the Mayo Clinic database and included (i) chronic phase MPN (MPN‐CP;… read more here.
Keywords: mut; risk factors; mtp53 mut; mpn ... See more keywords
The Mut+ strain of Komagataella phaffii (Pichia pastoris) expresses PAOX1 5 and 10 times faster than Muts and Mut− strains: evidence that formaldehyde or/and formate are true inducers of PAOX1
Sign Up to like & getrecommendations! Published in 2020 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-020-10793-8
Abstract: The methylotrophic yeast Komagataella phaffii is among the most popular hosts for recombinant protein synthesis. Most recombinant proteins have been expressed in the wild-type Mut+ host strain from the methanol-inducible alcohol oxidase (AOX) promoter PAOX1.… read more here.
Keywords: methanol; mut strain; komagataella phaffii; strain ... See more keywords
Sethoxydim-resistant mutants of the thermotolerant microalga Micractinium sp. accumulate significant amounts of triacylglycerol in non-stressful conditions
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Phycology"
DOI: 10.1007/s10811-019-01859-w
Abstract: Because of their high lipid content, microalgae are regarded as a potentially competitive source for biofuels. However, one of the main biotechnological challenges in algae-based biofuels is that cell division is arrested under conditions which… read more here.
Keywords: mutants thermotolerant; sethoxydim resistant; mut; resistant mutants ... See more keywords
Ag@MUT-16 nanocomposite as a Fenton-like and plasmonic photocatalyst for degradation of Quinoline Yellow under visible light.
Sign Up to like & getrecommendations! Published in 2024 at "Dalton transactions"
DOI: 10.1039/d4dt00322e
Abstract: A new cobalt-based metal-organic framework with the chemical formula of [Co2(DClTPA)2(DABCO)]·(DMF)4 (MUT-16) containing 1,4-diazabicyclo[2.2.2]octane (DABCO) and 2,5-dichloroterephthalic acid (DClTPA) has been designed and prepared through a solvothermal method. MUT-16 (MUT = Materials from University of… read more here.
Keywords: mut; quinoline yellow; degradation quinoline; mut nanocomposite ... See more keywords
rGO/MUT-15 nanocomposite as a Fenton-like photocatalyst for the degradation of Acid Yellow 73 under visible light.
Sign Up to like & getrecommendations! Published in 2024 at "Dalton transactions"
DOI: 10.1039/d4dt01201a
Abstract: The Fenton-like reaction is an advanced oxidation process (AOP) used to effectively eliminate organic pollutants. Fenton-like materials include metal-organic frameworks (MOFs) containing Fe, Co, Mn, and Cu metal ions. MOF-based photocatalysts with the highest performance… read more here.
Keywords: rgo mut; mut nanocomposite; mut; fenton like ... See more keywords
149. Extraction-free RT-PCR to Detect SARS-CoV-2 Variants of Concern
Sign Up to like & getrecommendations! Published in 2021 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofab466.149
Abstract: Abstract Background SARS-CoV-2 variants of concern (VOC) have challenged real-time reverse transcriptase polymerase chain reaction (RT-PCR) methods for the diagnosis of COVID-19. Methods The CDC 2019-Novel Coronavirus real-time RT-PCR panel was modified to create a… read more here.
Keywords: sars cov; pcr; cov variants; mut ... See more keywords
Permittivity Measurement From 40 to 70 GHz Using a DC FPOR With a Fixed Specimen Holder and an Off-Axial Feed
Sign Up to like & getrecommendations! Published in 2024 at "IEEE Transactions on Microwave Theory and Techniques"
DOI: 10.1109/tmtt.2023.3337429
Abstract: This article proposes a double-concave (DC) Fabry–Perot open resonator (FPOR) to measure the complex permittivity of a material under test (MUT) in the band from 40 to 70 GHz. The resonator is fed by waveguides… read more here.
Keywords: ghz; mut; position; permittivity ... See more keywords
Abstract CT082: Capmatinib inMETex14-mutated (mut) advanced non-small cell lung cancer (NSCLC): Results from the phase II GEOMETRYmono-1study, including efficacy in patients (pts) with brain metastases (BM)
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-ct082
Abstract: Background: Capmatinib is a highly selective and potent MET inhibitor that crosses the blood-brain barrier. In the GEOMETRY mono-1 study, capmatinib showed clinically meaningful response rates in pts with advanced NSCLC harboring METex14 skipping mutations,… read more here.
Keywords: capmatinib; efficacy; mut; geometry ... See more keywords
Abstract 4142930: Title: Loss of estrogen receptor α causes early onset of right ventricular capillary rarefaction in female rats with experimental pulmonary hypertension
Sign Up to like & getrecommendations! Published in 2024 at "Circulation"
DOI: 10.1161/circ.150.suppl_1.4142930
Abstract: Background: Right ventricular failure (RVF) determines survival in patients with pulmonary hypertension (PH). Insufficient angiogenesis and impaired RV endothelial cell (RVEC) function are key contributors of RVF development. Female patients with PH have better RV… read more here.
Keywords: loss; capillary rarefaction; mut; function ... See more keywords
Mutant Idh1 Blocks Neutrophil Maturation By Repressing Myeloid Progenitor Programs
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DOI: 10.1182/blood-2024-210352
Abstract: Mutations of Isocitrate dehydrogenase 1 (IDH1) are found in several malignancies, including myelodysplastic neoplasms (MDS) and acute myeloid leukemia (AML). Despite rarely being detected in clonal hematopoiesis, IDH1 mutations are considered to be early pathogenetic… read more here.
Keywords: idh1 mut; mut; idh1 r132h; aml ... See more keywords
DNMT3A and NPM1 co-mutations in Acute Myeloid Leukemia (AML): A genomic landscape study
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DOI: 10.1182/blood-2025-1722
Abstract: Background: Independent genomic alterations (GA) in the DNMT3A and NPM1 genes occur frequently in AML. While NPM1 mutation carries favorable prognosis in AML and has emerged as a target for anti-menin based treatments, co-mutation with… read more here.
Keywords: mut; dnmt3a npm1; aml; aml cases ... See more keywords