Evaluation of the mutagenic effects of Molnupiravir and N4‐hydroxycytidine in bacterial and mammalian cells by HiFi sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22510
Abstract: Molnupiravir (MOV) is used to treat COVID‐19. In cells, MOV is converted to the ribonucleoside analog N4‐hydroxycytidine (NHC) and incorporated into the SARS‐CoV‐2 RNA genome during its replication, resulting in RNA mutations. The widespread accumulation… read more here.
Keywords: molnupiravir hydroxycytidine; mutagenic effects; effects molnupiravir; evaluation mutagenic ... See more keywords
Chemical characterization and cytotoxic, genotoxic, and mutagenic properties of Baccharis trinervis (Lam, Persoon) from Colombia and Brazil.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2017.10.027
Abstract: PHARMACOLOGY RELEVANCE Baccharis trinervis (Lam, Persoon) leaves are used in the traditional medicine for the treatment of high fevers, edema, inflammation, sores and muscle cramps, snakebites and as antiseptic. AIM OF THE STUDY To investigate… read more here.
Keywords: genotoxic mutagenic; colombia; mutagenic effects; cytotoxic genotoxic ... See more keywords
Simulated space radiation-induced mutants in the mouse kidney display widespread genomic change
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DOI: 10.1371/journal.pone.0180412
Abstract: Exposure to a small number of high-energy heavy charged particles (HZE ions), as found in the deep space environment, could significantly affect astronaut health following prolonged periods of space travel if these ions induce mutations… read more here.
Keywords: mutagenic effects; space; genomic change; mouse kidney ... See more keywords
A review on genotoxic and mutagenic effects of monoterpenes
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DOI: 10.14419/ijm.v5i2.8035
Abstract: This review sketches genotoxic and mutagenic potentials of monoterpenes, which find outs some important genotoxic, mutagenic as well as non-genotoxic and non-mutagenic monoterpenes. Monoterpenes are the important natural products. read more here.
Keywords: genotoxic mutagenic; mutagenic effects; effects monoterpenes; review genotoxic ... See more keywords
Genotoxic and mutagenic effects of polluted surface water in the midwestern region of Brazil using animal and plant bioassays
Sign Up to like & getrecommendations! Published in 2017 at "Genetics and Molecular Biology"
DOI: 10.1590/1678-4685-gmb-2015-0223
Abstract: Abstract This study aimed to evaluate DNA damage in animal and plant cells exposed to water from the Água Boa stream (Dourados, Mato Grosso do Sul, Brazil) by using bioassays, and to identify the chemical… read more here.
Keywords: mutagenic effects; water; brazil using; animal plant ... See more keywords