Articles with "mutant alleles" as a keyword



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Skin colour, carotenogenesis and chlorophyll degradation mutant alleles: genetic orchestration behind the fruit colour variation in tomato.

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Published in 2021 at "Plant cell reports"

DOI: 10.1007/s00299-020-02650-9

Abstract: The genetics underlying the fruit colour variation in tomato is an interesting area of both basic and applied research in plant biology. There are several factors, like phytohormones, environmental signals and epistatic interactions between genes,… read more here.

Keywords: fruit; fruit colour; variation tomato; mutant alleles ... See more keywords
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Accurate Detection of Rare Mutant Alleles by Target Base-Specific Cleavage with the CRISPR/Cas9 System.

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Published in 2021 at "ACS synthetic biology"

DOI: 10.1021/acssynbio.1c00056

Abstract: The detection of low-frequency somatic mutations enables early diagnosis of disease; however, base-substitution errors that arise during genomic library preparation and high-throughput sequencing can lead to false diagnostic information. To discriminate true genomic alterations from… read more here.

Keywords: mutant alleles; detection; cleavage; base ... See more keywords
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Accelerating Discovery of Functional Mutant Alleles in Cancer.

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Published in 2018 at "Cancer discovery"

DOI: 10.1158/2159-8290.cd-17-0321

Abstract: Most mutations in cancer are rare, which complicates the identification of therapeutically significant mutations and thus limits the clinical impact of genomic profiling in patients with cancer. Here, we analyzed 24,592 cancers including 10,336 prospectively… read more here.

Keywords: mutant alleles; accelerating discovery; discovery functional; functional mutant ... See more keywords
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Functional Divergence of G and Its Homologous Genes for Green Pigmentation in Soybean Seeds

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Published in 2022 at "Frontiers in Plant Science"

DOI: 10.3389/fpls.2021.796981

Abstract: The degradation of chlorophyll in mature soybean seeds is closely related to the development of their yellow color. In this study, we examined G, its homologue G-like (GL), and their mutant alleles and investigated the… read more here.

Keywords: chlorophyll; soybean seeds; soybean; mutant alleles ... See more keywords
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Does improved oleic acid content due to marker-assisted introgression of ahFAD2 mutant alleles in peanuts alter its mineral and vitamin composition?

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Published in 2022 at "Frontiers in Plant Science"

DOI: 10.3389/fpls.2022.942617

Abstract: Peanuts (Arachis hypogaea L.) with high oleic acid content have extended shelf life and several health benefits. Oleic, linoleic, and palmitic acid contents in peanuts are regulated by ahFAD2A and ahFAD2B mutant alleles. In the… read more here.

Keywords: introgression; acid; mutant alleles; oleic acid ... See more keywords