Articles with "mutant astrocytomas" as a keyword



SURG-42. THE T1/T2 RATIO IS ASSOCIATED WITH RESECTABILITY IN PATIENTS WITH IDH-MUTANT ASTROCYTOMAS CNS WHO GRADES 2 AND 3

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Published in 2024 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noae165.1121

Abstract: IDH-mutant astrocytomas CNS WHO grade 2 and 3 show heterogenous appearance on magnetic resonance imaging (MRI). In the pre-molecular era, the discrepancy between T1 hypointense and T2 hyperintense tumor volume in absolute values has been… read more here.

Keywords: patients idh; associated resectability; ratio; mutant astrocytomas ... See more keywords

The role of apparent diffusion coefficient in the grading of adult isocitrate dehydrogenase-mutant astrocytomas: relationship with the Ki-67 proliferation index

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Published in 2024 at "Acta Radiologica"

DOI: 10.1177/02841851241242653

Abstract: Background The grading of adult isocitrate dehydrogenase (IDH)-mutant astrocytomas is a crucial prognostic factor. Purpose To investigate the value of conventional magnetic resonance imaging (MRI) features and apparent diffusion coefficient (ADC) in the grading of… read more here.

Keywords: grading adult; mutant astrocytomas; proliferation index;

Association of MGMT status with survival in low and high-grade IDH-mutant astrocytomas.

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Published in 2025 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2025.43.16_suppl.2065

Abstract: 2065 Background: The role of MGMT promoter methylation status on survival for IDH-mutant astrocytomas is less known than for glioblastoma, IDH-wildtype (GBM). Further, different laboratories utilize a variety of techniques to measure methylation of the… read more here.

Keywords: survival; mutant astrocytomas; idh; mgmt ... See more keywords

Clinical and VASARI Features to Predict CDKN2A/B Homozygous Deletion in IDH-Mutant Astrocytomas: A Multicenter Study

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Published in 2025 at "American Journal of Neuroradiology"

DOI: 10.3174/ajnr.a8861

Abstract: BACKGROUND AND PURPOSE: Cyclin-dependent kinase inhibitor (CDKN)2A/B homozygous deletion holds an important value in the prognostic analysis of isocitrate dehydrogenase (IDH)-mutant astrocytomas. This study aimed to develop and validate a prediction model based on clinical… read more here.

Keywords: deletion; mutant astrocytomas; homozygous deletion; idh mutant ... See more keywords

Qualitative and Quantitative Magnetic Resonance Imaging Phenotypes May Predict CDKN2A/B Homozygous Deletion Status in Isocitrate Dehydrogenase-Mutant Astrocytomas: A Multicenter Study

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Published in 2023 at "Korean Journal of Radiology"

DOI: 10.3348/kjr.2022.0732

Abstract: Objective Cyclin-dependent kinase inhibitor (CDKN)2A/B homozygous deletion is a key molecular marker of isocitrate dehydrogenase (IDH)-mutant astrocytomas in the 2021 World Health Organization. We aimed to investigate whether qualitative and quantitative MRI parameters can predict… read more here.

Keywords: deletion; isocitrate dehydrogenase; homozygous deletion; mutant astrocytomas ... See more keywords