Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells
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DOI: 10.1182/blood-2019-125472
Abstract: Paraspeckles are sub-nuclear structures found in the interchromatin space of mammalian cells. The core paraspeckle components include a lncRNA NEAT1 and members of the DBHS family of proteins: NONO, SFPQ, and PSPC1. Paraspeckles and their… read more here.
Keywords: asxl1 hspcs; mutant asxl1; asxl1; paraspeckle formation ... See more keywords